# 2025-00730: Diisononyl Phthalate (DINP); Risk Evaluation Under the Toxic Substances Control Act; Notice of Availability

2025-00730, Diisononyl Phthalate (DINP); Risk Evaluation Under the Toxic Substances Control Act; Notice of Availability, is a Federal Register notice from an unnamed agency published 2025-01-15, effective Federal Register publication: January 15, 2025; document dated January 7, 2025; PRIA reads it as touching household money (as of 2026-06-08).

- Canonical: https://policyrisk.com/federal-register/2025-00730
- As of: 2026-06-08
- Plain-text twin of the page above; the HTML and this file carry the same facts.

## Facts
- Document number: 2025-00730
- Title: Diisononyl Phthalate (DINP); Risk Evaluation Under the Toxic Substances Control Act; Notice of Availability
- Type: Notice
- Agencies: unknown
- Citation: unknown
- Published: 2025-01-15
- Effective: Federal Register publication: January 15, 2025; document dated January 7, 2025
- Comments close: not stated
- Significant: no
- Touches household money: yes
- Regulation identifier numbers: none
- Last updated: 2026-06-08

## Summary

The EPA has finished checking the safety of a chemical called DINP and found it can harm people’s health. Companies that make, use, or handle DINP will soon face new rules to keep everyone safe. These changes could affect how DINP is made and used, so businesses should get ready to follow the new safety steps.

## Abstract

The Environmental Protection Agency (EPA or Agency) is announcing the availability of the final risk evaluation under the Toxic Substances Control Act (TSCA) for diisononyl phthalate (DINP) (1,2-Benzene- dicarboxylic acid, 1,2- diisononyl ester) (CASRN 28553- 12-0). The purpose of risk evaluations under TSCA is to determine whether a chemical substance presents an unreasonable risk of injury to health or the environment under the conditions of use, including unreasonable risk to potentially exposed or susceptible subpopulations identified as relevant to the risk evaluation by EPA, and without consideration of costs or non-risk factors. EPA used the best available science to prepare this final risk evaluation and determined, based on the weight of scientific evidence, that DINP poses unreasonable risk to human health. Under TSCA, EPA must initiate risk management actions to address the unreasonable risk.

## Effects PRIA read

- EPA: DINP Unsafe — Rules Coming: cost, medium. The EPA says diisononyl phthalate (DINP, CASRN 28553-12-0 and 68515-48-0) poses an unreasonable risk to human health and must begin risk management under TSCA section 6(a). EPA will propose regulatory actions affecting manufacture (including import), processing, distribution in commerce, commercial…
- Spray-Use Workers Face Health Risk: benefit, high. EPA identified that spray application of adhesives, sealants, or paints and coatings containing DINP can create high inhalation exposure and that female workers of reproductive age face developmental toxicity from acute inhalation; workers also face liver effects from chronic exposures. EPA says it…
- Adult Consumers: Liver-Effect Risk Identified: benefit, medium. EPA found the chronic liver effects associated with DINP are relevant to adult consumers and the adult general population (but not to infants and children). This finding means EPA may take steps that could change consumer products or their availability to address adult exposure.
- Upstream Firms Could Be Regulated: cost, medium. EPA may regulate upstream activities (for example, processing or distribution in commerce) to address downstream consumer or worker uses that drive the unreasonable risk, even if those upstream activities were not identified as driving the risk. That means importers, processors, and distributors co…

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## Sources
- [2025-00730 on federalregister.gov](https://www.federalregister.gov/documents/2025/01/15/2025-00730/diisononyl-phthalate-dinp-risk-evaluation-under-the-toxic-substances-control-act-notice-of)
- [2025-00730 as published (PDF)](https://www.govinfo.gov/content/pkg/FR-2025-01-15/pdf/2025-00730.pdf)

## Related
- [Previous: 2025-00729, Proposed Collection; Comment Request](https://policyrisk.com/federal-register/2025-00729)
- [Next: 2025-00733, Notice of Intent To Prepare an Environmental Impact Statement for the Proposed…](https://policyrisk.com/federal-register/2025-00733)
- [All Federal Register documents](https://policyrisk.com/federal-register)

Source: PRIA, https://policyrisk.com/federal-register/2025-00730 (as of 2026-06-08).
