# 2025-04257: Pfizer's Phthalimido Lactol: Duty-Free Drug Magic in Michigan?

2025-04257, Foreign-Trade Zone (FTZ) 43, Notification of Proposed Production Activity; Pfizer, Inc.; (Pharmaceutical Intermediate Product); Kalamazoo, Michigan, is a Federal Register notice from Commerce Department, Foreign-Trade Zones Board published 2025-03-17, effective The closing period for their receipt is April 28, 2025. (as of 2026-06-08).

- Canonical: https://policyrisk.com/federal-register/2025-04257
- As of: 2026-06-08
- Plain-text twin of the page above; the HTML and this file carry the same facts.

## Facts
- Document number: 2025-04257
- Title: Foreign-Trade Zone (FTZ) 43, Notification of Proposed Production Activity; Pfizer, Inc.; (Pharmaceutical Intermediate Product); Kalamazoo, Michigan
- Type: Notice
- Agencies: Commerce Department; Foreign-Trade Zones Board
- Citation: 90 FR 12294
- Published: 2025-03-17
- Effective: The closing period for their receipt is April 28, 2025.
- Comments close: not stated
- Significant: no
- Touches household money: no
- Regulation identifier numbers: none
- Last updated: 2026-06-08

## In one line

Pfizer's Phthalimido Lactol: Duty-Free Drug Magic in Michigan?

## Summary

Pfizer wants to make a new pharmaceutical ingredient called phthalimido lactol at its Kalamazoo, Michigan plant using a special foreign material called 3-PPA. This change could save Pfizer money on import duties thanks to Foreign-Trade Zone rules. People have until April 28, 2025, to share their thoughts on this plan.

## Effects PRIA read

No economic effects identified for this document.

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## Sources
- [2025-04257 on federalregister.gov](https://www.federalregister.gov/documents/2025/03/17/2025-04257/foreign-trade-zone-ftz-43-notification-of-proposed-production-activity-pfizer-inc-pharmaceutical)
- [2025-04257 as published (PDF)](https://www.govinfo.gov/content/pkg/FR-2025-03-17/pdf/2025-04257.pdf)

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Source: PRIA, https://policyrisk.com/federal-register/2025-04257 (as of 2026-06-08).