# 2025-08607: CMS Seeks Comments on Medicare Drug Price Negotiations

2025-08607, Medicare Program; Inflation Reduction Act (IRA) Medicare Drug Price Negotiation Program Draft Guidance; Comment Request, is a Federal Register notice from Health and Human Services Department, Centers for Medicare & Medicaid Services published 2025-05-15, effective for 2026, 2027, and 2028; PRIA reads it as touching household money (as of 2026-10-20).

- Canonical: https://policyrisk.com/federal-register/2025-08607
- As of: 2026-10-20
- Plain-text twin of the page above; the HTML and this file carry the same facts.

## Facts
- Document number: 2025-08607
- Title: Medicare Program; Inflation Reduction Act (IRA) Medicare Drug Price Negotiation Program Draft Guidance; Comment Request
- Type: Notice
- Agencies: Health and Human Services Department; Centers for Medicare & Medicaid Services
- Citation: 90 FR 20674
- Published: 2025-05-15
- Effective: for 2026, 2027, and 2028
- Comments close: not stated
- Significant: no
- Touches household money: yes
- Regulation identifier numbers: none
- Last updated: 2026-10-20

## In one line

CMS Seeks Comments on Medicare Drug Price Negotiations

## Summary

CMS is rolling out draft rules for the Medicare Drug Price Negotiation Program under the Inflation Reduction Act. This affects drug makers and Medicare by setting fair maximum prices for certain costly drugs from 2026 to 2028, aiming to save money for patients and taxpayers. Public comments are open until June 26, 2025, so everyone can weigh in before these changes kick in.

## Abstract

The Centers for Medicare & Medicaid Services (CMS) is announcing an opportunity for the public to comment on CMS' draft guidance for the third cycle of the Medicare Drug Price Negotiation Program, the first cycle of renegotiation, and manufacturer effectuation of the maximum fair price for 2026, 2027, and 2028 for the implementation of the Inflation Reduction Act (IRA).

## Effects PRIA read

- Medicare drug prices capped 2026–2028: benefit, medium. You (Medicare patients) are affected by new Medicare Drug Price Negotiation Program rules that set a "maximum fair price" for certain medicines for 2026, 2027, and 2028. CMS says the changes aim to lower medicine costs and make medicines more affordable, and CMS is seeking public comment on draft g…
- Manufacturers must effectuate fair prices: cost, medium. If you are a drug manufacturer, CMS' draft guidance covers manufacturer effectuation of the "maximum fair price" and negotiation cycles for drugs for 2026, 2027, and 2028. The guidance applies to drug makers as CMS implements the Inflation Reduction Act negotiation and renegotiation process for tho…

## Related documents

- [2026-20281](https://policyrisk.com/federal-register/2026-20281): Global Benchmark for Efficient Drug Pricing (GLOBE) Model, 2026-10-02
- [2026-20131](https://policyrisk.com/federal-register/2026-20131): Medicare Program; Inpatient Rehabilitation Facility Prospective Payment System for Federal Fiscal Year 2027 and Updates to the IRF Quality…, 2026-10-01
- [2026-20067](https://policyrisk.com/federal-register/2026-20067): Medicare Program; FY 2027 Hospice Wage Index and Payment Rate Update and Hospice Quality Reporting Program Requirements; Correction, 2026-09-30
- [2026-19959](https://policyrisk.com/federal-register/2026-19959): Medicare Program; Prospective Payment System and Consolidated Billing for Skilled Nursing Facilities; Updates to the Quality Reporting Prog…, 2026-09-30
- [2026-19946](https://policyrisk.com/federal-register/2026-19946): Medicare Program; Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals (IPPS) and the Long-Term Care Hospital Prospectiv…, 2026-09-29
- [2026-15652](https://policyrisk.com/federal-register/2026-15652): Medicare Program; Inpatient Rehabilitation Facility Prospective Payment System for Federal Fiscal Year 2027 and Updates to the IRF Quality…, 2026-08-03

## Sources
- [2025-08607 on federalregister.gov](https://www.federalregister.gov/documents/2025/05/15/2025-08607/medicare-program-inflation-reduction-act-ira-medicare-drug-price-negotiation-program-draft-guidance)
- [2025-08607 as published (PDF)](https://www.govinfo.gov/content/pkg/FR-2025-05-15/pdf/2025-08607.pdf)

## Related
- [Previous: 2025-08606, List of Correspondence From January 1, 2024, Through December 31, 2024](https://policyrisk.com/federal-register/2025-08606)
- [Next: 2025-08608, Southern Nuclear Operating Company, Inc.; Vogtle Electric Generating Plant, Uni…](https://policyrisk.com/federal-register/2025-08608)
- [All Federal Register documents](https://policyrisk.com/federal-register)

Source: PRIA, https://policyrisk.com/federal-register/2025-08607 (as of 2026-10-20).