# 2025-21665: President Unleashes AI 'Genesis Mission' for Science Revolution

2025-21665, Launching the Genesis Mission, is a Federal Register presidential document from Executive Office of the President published 2025-11-28, effective 2025-11-24 (as of 2026-11-03).

- Canonical: https://policyrisk.com/federal-register/2025-21665
- As of: 2026-11-03
- Plain-text twin of the page above; the HTML and this file carry the same facts.

## Facts
- Document number: 2025-21665
- Title: Launching the Genesis Mission
- Type: Presidential Document
- Agencies: Executive Office of the President
- Citation: 90 FR 55035
- Published: 2025-11-28
- Effective: 2025-11-24
- Comments close: not stated
- Significant: no
- Touches household money: no
- Regulation identifier numbers: none
- Last updated: 2026-11-03

## In one line

President Unleashes AI 'Genesis Mission' for Science Revolution

## Summary

The Genesis Mission is a bold new national effort to use artificial intelligence (AI) to speed up scientific discoveries and solve big challenges. It brings together top scientists, businesses, universities, and government resources to build powerful AI tools using decades of federal data. This mission aims to boost America’s innovation, security, and economy, with investments starting now and lasting for years to come.

## Effects PRIA read

- New Federal AI Science Platform Access: benefit, medium. The Department of Energy will build the American Science and Security Platform to provide high-performance computing, AI models, and secure access to proprietary, federally curated, and open scientific datasets. The Secretary must identify computing, storage, and networking resources within 90 days…
- Fellowships, Internships, Apprenticeships at DOE Labs: benefit, medium. The order directs creation of competitive fellowships, internships, and apprenticeships focused on applying AI to the Mission's science challenges, including placement of participants at DOE national laboratories. These programs will be established consistent with existing statutes and subject to a…
- Funding Opportunities and Prize Competitions: benefit, medium. Participating agencies, coordinated through the NSTC, may launch coordinated funding opportunities or prize competitions to incentivize private-sector participation in AI-driven scientific research, subject to applicable law and available appropriations.
- Clear IP and Commercialization Policies: benefit, medium. The Secretary will establish clear policies for ownership, licensing, trade-secret protections, and commercialization of intellectual property developed under the Mission, including innovations from AI-directed experiments.
- Data-Access, Cybersecurity, and Vetting Rules: benefit, low. The Mission will require uniform and stringent data access, data-management, and cybersecurity processes for non-Federal collaborators, and will establish procedures for vetting and authorizing users who seek access to Platform resources and datasets.

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## Sources
- [2025-21665 on federalregister.gov](https://www.federalregister.gov/documents/2025/11/28/2025-21665/launching-the-genesis-mission)
- [2025-21665 as published (PDF)](https://www.govinfo.gov/content/pkg/FR-2025-11-28/pdf/2025-21665.pdf)

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Source: PRIA, https://policyrisk.com/federal-register/2025-21665 (as of 2026-11-03).