# 2026-00628: EPA Establishes Safe Limits for Pyriofenone on Produce

2026-00628, Pyriofenone; Pesticide Tolerances, is a Federal Register rule from Environmental Protection Agency published 2026-01-14, effective 2026-01-14 (as of 2026-06-11).

- Canonical: https://policyrisk.com/federal-register/2026-00628
- As of: 2026-06-11
- Plain-text twin of the page above; the HTML and this file carry the same facts.

## Facts
- Document number: 2026-00628
- Title: Pyriofenone; Pesticide Tolerances
- Type: Rule
- Agencies: Environmental Protection Agency
- Citation: 91 FR 1392
- Published: 2026-01-14
- Effective: 2026-01-14
- Comments close: not stated
- Significant: no
- Touches household money: no
- Regulation identifier numbers: none
- Last updated: 2026-06-11

## In one line

EPA Establishes Safe Limits for Pyriofenone on Produce

## Summary

The EPA just set safe limits for pyriofenone pesticide residues on apples, berries, and cherries, helping farmers and food makers know the rules. These new limits start January 14, 2026, and anyone who disagrees has until March 16, 2026, to speak up. This move keeps our food safe without slowing down farming or food production.

## Abstract

This regulation establishes tolerances for residues of pyriofenone in or on apple; apple, wet pomace; berry, low growing, subgroup 13-07G (except cranberry); and cherry subgroup 12-12A. ISK Biosciences Corporation requested these tolerances under the Federal Food, Drug, and Cosmetic Act (FFDCA).

## Effects PRIA read

- New pyriofenone residue limits: benefit, medium. EPA established legal residue limits for pyriofenone on specific commodities effective January 14, 2026: apple at 0.3 ppm; apple, wet pomace at 0.5 ppm; berry, low growing, subgroup 13-07G (except cranberry) at 2.0 ppm; and cherry subgroup 12-12A at 1.5 ppm. The rule notes it applies to agricultura…
- EPA finds tolerances safe for consumers: benefit, medium. EPA concluded there is a reasonable certainty of no harm from aggregate pyriofenone residues to the general population and to infants and children, and classified pyriofenone as "Not Likely to Be Carcinogenic to Humans." EPA's chronic assessment indicates children 1-2 years old would use 9.2% of th…
- Children's safety factor set to 1X: mixed, low. EPA continued its determination to reduce the Food Quality Protection Act (FQPA) safety factor for infants and children from the default 10X to 1X for pyriofenone, based on reliable data cited by the Agency. This reduction is part of EPA's calculation of safe exposure levels for children.
- Trade and exporters allowed adjustment time: benefit, low. For tolerance actions that lower or revoke existing tolerances, EPA will set an expiration date six months after publication to allow exporters affected by World Trade Organization Sanitary and Phytosanitary (SPS) requirements time to adapt. The rule notes Codex MRLs differ for low-growing berries…

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## Sources
- [2026-00628 on federalregister.gov](https://www.federalregister.gov/documents/2026/01/14/2026-00628/pyriofenone-pesticide-tolerances)
- [2026-00628 as published (PDF)](https://www.govinfo.gov/content/pkg/FR-2026-01-14/pdf/2026-00628.pdf)

## Related
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- [All Federal Register documents](https://policyrisk.com/federal-register)

Source: PRIA, https://policyrisk.com/federal-register/2026-00628 (as of 2026-06-11).