# 2026-12418: EPA Reviews Applications for New Pesticide Ingredients

2026-12418, Pesticide Product Registration; Receipt of Applications for New Active Ingredients (March 2026), is a Federal Register notice from Environmental Protection Agency published 2026-06-22, effective 2026-07-22; PRIA reads it as touching household money (as of 2026-06-29).

- Canonical: https://policyrisk.com/federal-register/2026-12418
- As of: 2026-06-29
- Plain-text twin of the page above; the HTML and this file carry the same facts.

## Facts
- Document number: 2026-12418
- Title: Pesticide Product Registration; Receipt of Applications for New Active Ingredients (March 2026)
- Type: Notice
- Agencies: Environmental Protection Agency
- Citation: 91 FR 37111
- Published: 2026-06-22
- Effective: 2026-07-22
- Comments close: 2026-07-22
- Significant: no
- Touches household money: yes
- Regulation identifier numbers: none
- Last updated: 2026-06-29

## In one line

EPA Reviews Applications for New Pesticide Ingredients

## Summary

The EPA just announced it’s reviewing new pesticide ingredients that aren’t in any products yet. If you’re a farmer, gardener, or pesticide maker, this could mean new options soon! You’ve got until July 22, 2026, to share your thoughts before decisions are made—so don’t miss out on having your say.

## Abstract

This document announces the Agency's receipt of and solicits comments on applications to register pesticide products containing active ingredients not included in any currently registered pesticide products. The Agency is providing this notice in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). EPA uses the month and year in the title to identify when the Agency complied with the applications identified in this notice of receipt. Unit II. of this document identifies certain applications received in 2024 and 2025 that are currently being evaluated by EPA, along with information about each application, including when it was received, who submitted the application, and the purpose of the application.

## Effects PRIA read

- Public comment period on new pesticide ingredients: benefit, low. The EPA is accepting public comments on applications to register pesticide products with active ingredients not yet in any registered products. Comments must be received on or before July 22, 2026, and the applications listed were received in 2024 and 2025.
- New skin-applied insect repellents filed: benefit, low. EPA received applications for skin-applied insect repellents (Citrepel Emulsion 20 and Incognito) containing Cymbopogon winterianus oil at 20.00%; the manufacturing use product Citrepel 75 lists the ingredient at 100.00%. These applications were received February 22, 2024, and are open for public c…
- Melatonin-based agricultural product applications: benefit, low. EPA received applications on March 29, 2024, for Melatonin Technical (melatonin at 99.7%) as a Manufacturing Use Product and for CHB-ST (GIM) and CHB-FNA containing melatonin at 1.0% as a Seed Treatment and a Plant Growth Regulator. These applications are open for comment through July 22, 2026.
- Ascr#18 plant defense product applications: benefit, low. EPA received applications on February 15, 2024, for products named Phytalix and ASCR #18 Technical containing Ascr#18 (one at 0.042% for foliar/seed use and a technical at 95.24%) proposed for on-farm, greenhouse, and commercial foliar and seed treatment to activate plant defense against fungal, vi…
- Gene-editing insecticide application (KNOCKOUT SWD): benefit, low. EPA received an application on August 6, 2025, for a product named KNOCKOUT SWD whose active ingredient is a complex consisting of loss-of-function edits to beta tub2 and sxl genes, gRNA, and the SpCas9 protein; the proposed use is as an insecticide. Comments are due by July 22, 2026.

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## Sources
- [2026-12418 on federalregister.gov](https://www.federalregister.gov/documents/2026/06/22/2026-12418/pesticide-product-registration-receipt-of-applications-for-new-active-ingredients-march-2026)
- [2026-12418 as published (PDF)](https://www.govinfo.gov/content/pkg/FR-2026-06-22/pdf/2026-12418.pdf)

## Related
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- [All Federal Register documents](https://policyrisk.com/federal-register)

Source: PRIA, https://policyrisk.com/federal-register/2026-12418 (as of 2026-06-29).