# 2026-19431: Feds License Protein That Skips Chemo for Stem Cell Transplants

2026-19431, Government-Owned Inventions; Availability for Licensing, is a Federal Register notice from Health and Human Services Department, National Institutes of Health published 2026-09-23; PRIA reads it as touching household money (as of 2026-09-30).

- Canonical: https://policyrisk.com/federal-register/2026-19431
- As of: 2026-09-30
- Plain-text twin of the page above; the HTML and this file carry the same facts.

## Facts
- Document number: 2026-19431
- Title: Government-Owned Inventions; Availability for Licensing
- Type: Notice
- Agencies: Health and Human Services Department; National Institutes of Health
- Citation: 91 FR 60382
- Published: 2026-09-23
- Effective: unknown
- Comments close: not stated
- Significant: no
- Touches household money: yes
- Regulation identifier numbers: none
- Last updated: 2026-09-30

## In one line

Feds License Protein That Skips Chemo for Stem Cell Transplants

## Summary

The government is offering a new invention for licensing that makes stem cell transplants safer and less harsh, especially for leukemia patients and older folks. This tech uses a special protein to prepare patients for transplants without the tough side effects of chemo and radiation. Companies can start licensing this preclinical innovation now to help bring better treatments to market faster.

## Abstract

The inventions listed below are owned by an agency of the U.S. Government and are available for licensing to achieve expeditious commercialization of results of federally-funded research for the benefit of the public health.

## Effects PRIA read

- Safer stem-cell transplant conditioning: benefit, medium. The NIH is offering patent rights for a preclinical therapy (DT390-biscFV(cMPL)) that can be used as a new conditioning regimen to make hematopoietic stem and progenitor cell (HSPC) transplants safer, especially for leukemia patients and older people who cannot tolerate chemo or radiation. The noti…
- Licensing and collaboration chance for developers: benefit, medium. The government is making patent rights available for licensing and commercial development for the DT390-biscFV(cMPL) technology (HHS Ref. No.: E-188-2021-0) and is seeking statements of capability or interest for collaborative research to further develop, evaluate, or commercialize it. Licensing co…

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## Sources
- [2026-19431 on federalregister.gov](https://www.federalregister.gov/documents/2026/09/23/2026-19431/government-owned-inventions-availability-for-licensing)
- [2026-19431 as published (PDF)](https://www.govinfo.gov/content/pkg/FR-2026-09-23/pdf/2026-19431.pdf)

## Related
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- [All Federal Register documents](https://policyrisk.com/federal-register)

Source: PRIA, https://policyrisk.com/federal-register/2026-19431 (as of 2026-09-30).