# 2026-22576: EPA requires advance notice before companies try new chemical uses 2026-22576, Significant New Use Rules on Certain Chemical Substances (25-3.5e), is a Federal Register rule from Environmental Protection Agency published 2026-11-05, effective 2027-01-04; PRIA reads it as touching household money (as of 2026-11-06). - Canonical: https://policyrisk.com/federal-register/2026-22576 - As of: 2026-11-06 - Plain-text twin of the page above; the HTML and this file carry the same facts. ## Facts - Document number: 2026-22576 - Title: Significant New Use Rules on Certain Chemical Substances (25-3.5e) - Type: Rule - Agencies: Environmental Protection Agency - Citation: 91 FR 69704 - Published: 2026-11-05 - Effective: 2027-01-04 - Comments close: not stated - Significant: no - Touches household money: yes - Regulation identifier numbers: 2070-AB27 - Last updated: 2026-11-06 ## In one line EPA requires advance notice before companies try new chemical uses ## Summary The EPA is rolling out new rules that make companies tell them 90 days before using certain chemicals in new ways. This gives the EPA time to check if those uses are safe before they start. These rules kick in on January 4, 2027, and affect anyone making or importing these chemicals, so plan ahead to avoid delays or extra costs! ## Abstract EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination. ## Effects PRIA read - 90‑Day Advance Notice Requirement: cost, high. If you manufacture, import, or process any listed chemical for a use designated as a "significant new use," you must notify EPA at least 90 days before starting that activity. EPA will review the notice and you may not begin the activity until EPA completes its review and any required follow-up; th… - Per‑Submission SNUN Costs and Fees: cost, high. EPA estimates preparing and submitting a SNUN costs about $45,000 for large businesses and about $14,500 for qualifying small businesses. The required user fee is $37,000 for large submitters or a reduced fee of $6,480 for qualifying small businesses. - Small‑Business Fee Relief Lowers Burden: benefit, medium. EPA offers a reduced SNUN user fee of $6,480 for qualifying small businesses (per 13 CFR 121.201), which EPA says reduces the total estimated per‑SNUN reporting and recordkeeping cost to about $14,500 for those firms. - Reporting Time Burden and Electronic Filing: cost, medium. Submitting a SNUN requires using EPA Form 7710‑25 via EPA's e‑PMN software and Central Data Exchange (CDX) registration; EPA estimates an annual burden averaging between 30 and 170 hours per SNUN submission. If a TSCA section 4 rule/order requires testing, that data must be submitted with the SNUN. - Export Notification One‑Time Cost: cost, low. If you export a chemical that is subject to a SNUR, you must provide a one‑time export notification to EPA for the first export or intended export to each country; EPA estimates the per‑notification cost is about $106. - Substance‑Specific Operational and Disposal Requirements: cost, medium. The rule imposes substance‑specific controls that can affect operations: examples include respirator protection factors (e.g., NIOSH APF ≥ 1000 for manganate(4-) and APF ≥ 10 for some substances), limits on dust filter changes (more than two times/year is a significant new use), requirements that o… - Cutoff Date for Ongoing Uses and Cease/Resume Rule: cost, medium. EPA designates June 5, 2026 as the cutoff date for determining whether a use is ongoing; if a person began a significant new use after publication of the proposed rule (June 5, 2026) and before the final rule becomes effective, they must cease that activity on the final rule's effective date and ma… ## Related documents - [2026-22082](https://policyrisk.com/federal-register/2026-22082): Additional Reconsideration Standards of Performance for New, Reconstructed, and Modified Sources and Emissions Guidelines for Existing Sour…, 2026-10-29 - [2026-21155](https://policyrisk.com/federal-register/2026-21155): Renewable Fuel Standard (RFS) Program: Reallocation of Additional 2025 Small Refinery Exemptions, 2026-10-16 - [2026-20849](https://policyrisk.com/federal-register/2026-20849): Clean Water Act Hazardous Substance Facility Response Plans: Compliance Date Delay and Changes To Reflect Administration Policy, 2026-10-13 - [2026-19072](https://policyrisk.com/federal-register/2026-19072): Rescission of the Greenhouse Gas Findings for Fossil Fuel-Fired Power Plants and Repeal of Regulations for Power Plant Greenhouse Gas Emiss…, 2026-09-17 - [2026-19071](https://policyrisk.com/federal-register/2026-19071): Partial Repeal of the Carbon Pollution Standards for Fossil Fuel-Fired Electric Generating Units, 2026-09-17 - [2026-18317](https://policyrisk.com/federal-register/2026-18317): Updated Definition of “Waters of the United States”, 2026-09-09 ## Sources - [2026-22576 on federalregister.gov](https://www.federalregister.gov/documents/2026/11/05/2026-22576/significant-new-use-rules-on-certain-chemical-substances-25-35e) - [2026-22576 as published (PDF)](https://www.govinfo.gov/content/pkg/FR-2026-11-05/pdf/2026-22576.pdf) ## Related - [Previous: 2026-22538, Treatment of Emergency Amendments: Paycheck Protection Program Liquidity Facili…](https://policyrisk.com/federal-register/2026-22538) - [Next: 2026-22584, Approval and Promulgation of State Plans for Designated Facilities and Pollutan…](https://policyrisk.com/federal-register/2026-22584) - [All Federal Register documents](https://policyrisk.com/federal-register) Source: PRIA, https://policyrisk.com/federal-register/2026-22576 (as of 2026-11-06).