2025-16646Notice

FDA Greenlights Withdrawal of ALS Drug RELYVRIO Packets

Published Date: 8/29/2025

Notice

Summary

Amylyx Pharmaceuticals asked the FDA to take back its approval for the drug RELYVRIO, used in 1g and 3g packets. This means RELYVRIO won’t be available as an FDA-approved treatment anymore. Patients and healthcare providers should watch for updates on how this change might affect treatment options and costs.

Analyzed Economic Effects

1 provisions identified: 0 benefits, 1 costs, 0 mixed.

RELYVRIO FDA Approval Withdrawn

If you take RELYVRIO, the FDA approval for RELYVRIO (sodium phenylbutyrate and taurursodiol) in 3 gram and 1 gram packets has been withdrawn at the drugmaker Amylyx Pharmaceuticals' request. This means RELYVRIO will no longer be an FDA-approved treatment; patients and healthcare providers should watch for updates about how this change might affect treatment options and costs.

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Key Dates

Published Date
8/29/2025

Department and Agencies

Department
Independent Agency
Agency
Health and Human Services Department
Food and Drug Administration
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