2025-20581Notice

CDC Seeks Comments on Continuing HIV Prevention Data Tracking

Published Date: 11/21/2025

Notice

Summary

The CDC wants your thoughts on their plan to keep collecting important HIV prevention data from health departments and community groups that get federal funding. This helps track how well HIV programs are working without adding extra paperwork. If you have ideas or concerns, send them in by January 20, 2026—this keeps the process smooth and saves money in the long run.

Analyzed Economic Effects

3 provisions identified: 0 benefits, 2 costs, 1 mixed.

Mandatory NHM&E Reporting by Grantees

If your organization is a health department or a community-based organization that receives federal funds for HIV prevention, CDC requires you to collect and report standardized HIV prevention program evaluation data to the National HIV Prevention Program Monitoring and Evaluation (NHM&E). CDC estimates the combined respondent burden at 204,498 annual hours and notes there are no additional costs to respondents other than their time; the current OMB approval expires 2028-01-31.

Data-Entry Options Differ by Grantee Type

Health Department grantees may either key-enter data or upload files to CDC's EvaluationWeb application, but Community-Based Organization (CBO) grantees may only key-enter data into the web application. This difference determines whether an organization can submit bulk uploads or must enter data manually.

Expanded and Updated Data Elements for HIV Programs

CDC's revision adds and updates the data elements grantees must report, including Race and Ethnicity updates aligned to OMB SPD-15, deletions/modifications per Executive Orders, changes to PrEP variables, and new variables for PEP, Mpox, syndemics, TB, hepatitis B and C, chlamydia, gonorrhea, syphilis testing/treatment/referral, Essential Support Services screening/referral/provision, and new jurisdiction-level aggregate variables. These changes change what information organizations must collect and report.

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Key Dates

Published Date
Comments Due
11/21/2025
1/20/2026

Department and Agencies

Department
Independent Agency
Agency
Health and Human Services Department
Centers for Disease Control and Prevention
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