DEA Plays Chemical Whack-A-Mole With Designer Drug CUMYL-PEGACLONE
Published Date: 12/11/2025
Proposed Rule
Summary
The Drug Enforcement Administration wants to make the temporary ban on CUMYL-PEGACLONE permanent by placing it in Schedule I, meaning it’s considered very risky and illegal to handle without special permission. This affects anyone who makes, sells, studies, or possesses this substance. Comments and hearing requests are open until January 12, 2026, so speak up before then!
Analyzed Economic Effects
3 provisions identified: 0 benefits, 3 costs, 0 mixed.
Unauthorized handling may bring penalties
The proposal says any activity with CUMYL-PEGACLONE that is not authorized under the Controlled Substances Act would be unlawful and may subject the person to administrative, civil, and/or criminal sanctions under Schedule I rules.
CUMYL-PEGACLONE moved to Schedule I
The Drug Enforcement Administration proposes to permanently place CUMYL-PEGACLONE (also called SGT-151) in Schedule I, making permanent the temporary controls first ordered on December 12, 2023. If finalized, anyone who manufactures, distributes, imports, exports, researches, or possesses this substance would be subject to the regulatory controls for Schedule I substances; comments are due January 12, 2026.
Required registrations, security, and controls
If finalized, anyone handling CUMYL-PEGACLONE must follow Schedule I requirements: register with DEA, meet Schedule I security rules, use specified labeling and packaging, comply with manufacturing quotas, keep initial and biennial inventories, maintain records and reports, use required order forms, and follow import/export controls.
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