2025-22680NoticeWallet

FDA Resurrects Vanished Birth Control Shot for Generic Copycats

Published Date: 12/12/2025

Notice

Summary

The FDA has decided that LUNELLE, a birth control shot, wasn’t taken off the market because it was unsafe or didn’t work. This means companies can now apply to make generic versions, which could make the shot more affordable and easier to get. Women who use or want this birth control might see more options soon, with no extra safety worries.

Analyzed Economic Effects

1 provisions identified: 1 benefits, 0 costs, 0 mixed.

Generic Approval Allowed for LUNELLE

FDA determined that LUNELLE (estradiol cypionate 5 mg/0.5 mL and medroxyprogesterone acetate 25 mg/0.5 mL) was not withdrawn from sale for reasons of safety or effectiveness. This decision (published December 12, 2025) allows companies to submit abbreviated new drug applications (ANDAs) referring to LUNELLE, and FDA may approve those ANDAs if they meet all other legal and regulatory requirements, so you may see generic versions become available.

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Key Dates

Published Date
12/12/2025

Department and Agencies

Department
Independent Agency
Agency
Health and Human Services Department
Food and Drug Administration
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