Title 42 › Chapter CHAPTER 23— - DEVELOPMENT AND CONTROL OF ATOMIC ENERGY › Subchapter SUBCHAPTER IX— - ATOMIC ENERGY LICENSES › § 2142
The Nuclear Regulatory Commission can only allow a reactor to use highly enriched uranium (HEU) as a target for making medical isotopes if two things are true. First, the NRC decides there is no workable non-HEU target for that reactor, and the person getting the license promises they will switch to a non-HEU target as soon as one can be used. Second, the Secretary of Energy must certify that the U.S. government is actively helping to develop such an alternative target for that reactor. An “alternative medical isotope production target” is one with less than 20 percent U–235. A target “can be used” if the Department of Energy’s Reduced Enrichment Research and Test Reactor Program has qualified it and using it would let the large majority of current and planned experiments and isotope production continue without a large percentage increase in the reactor’s total operating cost. “Highly enriched uranium” means 20 percent or more U–235. “Medical isotope” includes molybdenum-99, iodine-131, xenon-133, and other radioactive materials used to make radiopharmaceuticals for diagnosis, treatment, or research.
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The Public Health and Welfare — Source: USLM XML via OLRC
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42 U.S.C. § 2142
Title 42 — The Public Health and Welfare
Last Updated
Apr 6, 2026
Release point: 119-73