EPA Flags Risks in Cosmetics Chemical D4—Comments Needed
Published Date: 9/17/2025
Notice
Summary
The EPA just shared a draft report about a chemical called D4, which is used in things like cosmetics and personal care products. They found that D4 might be risky to people’s health and the environment and want your thoughts before making final decisions. If you make, use, or sell products with D4, now’s the time to speak up—this could lead to new rules and changes soon!
Analyzed Economic Effects
2 provisions identified: 0 benefits, 2 costs, 0 mixed.
EPA Finds D4 Presents Unreasonable Risk
The EPA published a draft risk evaluation under the Toxic Substances Control Act (TSCA) for Octamethylcyclotetrasiloxane (D4) (CASRN 556-67-2) and preliminarily determined, based on the weight of scientific evidence, that D4 poses an unreasonable risk to human health and the environment for certain conditions of use. The draft evaluation is open for public comment as a next step in the TSCA process.
Manufacturers and Sellers Should Act Now
The EPA is seeking public comment on the D4 draft risk evaluation, and the notice highlights that if you make, use, or sell products with D4 (for example in cosmetics or personal care products), now is the time to provide input. Stakeholders who make or sell products containing D4 may face future regulatory changes based on this evaluation.
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