EPA Lists New Chemicals for Review: Comments Due by Year's End
Published Date: 12/1/2025
Notice
Summary
The EPA just shared updates on new chemicals submitted for review between August and September 2025. If you make, import, or use new chemicals, this affects you—especially with deadlines to comment by December 31, 2025. Stay tuned for changes in approvals and testing that could impact your business timing and costs.
Analyzed Economic Effects
3 provisions identified: 2 benefits, 1 costs, 0 mixed.
TSCA Section 5 Notice Requirement Reminder
The notice reiterates that under TSCA section 5, any person who intends to manufacture (including import) a new chemical substance for a non-exempt commercial purpose, or to manufacture/process a substance for a use designated a significant new use, must submit a PMN, MCAN, or SNUN to EPA before starting the activity.
Deadline to Comment: Dec 31, 2025
The EPA is asking for public comments on new chemical submissions received from September 1 through September 30, 2025. Comments must be submitted to docket EPA-HQ-OPPT-2025-0067 on or before December 31, 2025, and you must follow EPA instructions for not submitting confidential business information online.
Public Status Reports on New Chemicals
EPA published non-CBI tables listing new chemical submissions received or under review for the period 9/1/2025 through 9/30/2025, including PMNs, SNUNs, MCANs, NOCs, and test information. The notice also points readers to EPA web pages and ChemView where case status, receipt dates, final determinations, and effective dates are available.
Personalized for You
How does this regulation affect your finances?
Personalize government policy and PRIA will tell you what this federal register document means for your household, plus every other regulation we track. PRIA reads each provision against your financial profile to show you exactly what matters to your wallet.
Key Dates
Department and Agencies
Related Federal Register Documents
2026-13667, Minor New Source Review Program Air Permitting Public Participation Requirements for State Implementation Plans
The EPA wants to give states more freedom to decide how much public input is needed when approving small air pollution sources or changes. This means local air agencies can tailor public participation to fit their community’s needs while still protecting air quality. If you’re involved in air permits, watch for comment deadlines and possible virtual hearings this summer!
2026-13263, Revisions To Establish the Sixth Unregulated Contaminant Monitoring Rule (UCMR 6) for Public Water Systems
The EPA is rolling out the sixth Unregulated Contaminant Monitoring Rule (UCMR 6) to check for new, sneaky chemicals in public drinking water. Big water systems serving 3,300+ people and some smaller ones will test for 30 different contaminants, including certain PFAS and pesticides, to keep our water safe. Comments and feedback are open until late August 2026, and the EPA will host fun online meetings to chat about the plan!
2026-12927, U.S. Ecology Nevada, Inc. High Mercury Subcategory Wastes Land Disposal Restrictions Variance
The EPA is giving U.S. Ecology Nevada a special green light to handle and dispose of high-mercury waste a bit differently than usual. This means mercury waste treated in Pennsylvania can now be safely sent to U.S. Ecology’s Nevada site for disposal under new rules starting July 27, 2026. This change helps protect people and the environment while keeping mercury waste management efficient and cost-effective.
2026-11047, National Emission Standards for Hazardous Air Pollutants From Hazardous Waste Combustors: Residual Risk and Technology Review
The EPA just updated rules for places that burn hazardous waste, like incinerators and boilers, to keep the air safe and clean. They confirmed current standards work well but added new limits on harmful gases like hydrogen fluoride and hydrogen cyanide. These changes start June 3, 2026, and include easier electronic reporting and some new rules for startup and shutdown times—helping protect health without big costs.
2026-10641, Hazardous and Solid Waste Management System: Disposal of Coal Combustion Residuals From Electric Utilities; Federal CCR Permit Program; Reopening of Comment Period
The EPA is reopening the comment period until June 29, 2026, for its proposed rule to create a federal permit program for safely disposing of coal ash from power plants. This affects electric utilities that handle coal waste and aims to improve environmental safety while possibly impacting their costs. Now’s the time for everyone to share their thoughts and help shape the rules!
2026-10387, Phasedown of Hydrofluorocarbons: Reconsideration of Certain Regulatory Requirements Promulgated Under the Technology Transitions Provisions of the American Innovation and Manufacturing Act of 2020
The EPA is updating rules to phase down hydrofluorocarbons (HFCs), chemicals used in cooling systems like refrigerators and air conditioners. These changes affect businesses in refrigeration, supermarkets, semiconductor manufacturing, and more, allowing some older equipment made before 2025 to keep running. The new rules kick in on July 27, 2026, helping industries transition smoothly while cutting harmful emissions.
Previous / Next Documents
Previous: 2025-21672, Information Collection Request to Office of Management and Budget; OMB Control Number: 1625-0003
The U.S. Coast Guard wants to keep collecting boating accident reports using the same form, with no changes. They’re asking the public to share thoughts by January 30, 2026, before they ask the government to approve this again. This helps keep boating safer without adding extra paperwork or costs.
Next: 2025-21674, Certain New Chemicals; Receipt and Status Information for July-August 2025
The EPA just shared updates on new chemicals submitted for review between July and August 2025. If you make, use, or sell chemicals, this affects you because the EPA is checking safety and asking for comments by December 31, 2025. Staying in the loop helps businesses avoid surprises and keep things running smoothly without extra costs or delays.