Painkiller Producer Wants Big Batches: Comment on Oxycodone Plans

2026-09566 — Schedules of Controlled Substances: Placement of CUMYL-PEGACLONE in Schedule I

Starting May 13, 2026, the DEA officially puts CUMYL-PEGACLONE—a chemical often linked to illegal drug use—into Schedule I, the strictest drug category. This means anyone making, selling, or using it faces serious legal rules and penalties. This move helps the U.S. follow international drug laws and keeps communities safer without adding new costs.

2026-08588 — Bulk Manufacturer of Controlled Substances Application: Patheon API Inc.

Patheon API Inc. wants to make large amounts of special research drugs like dimethyltryptamine and psilocybin. This affects researchers and companies involved in clinical trials, with a chance to comment or ask for a hearing by July 6, 2026. No money changes are mentioned, but the registration could speed up important drug studies.

2026-08595 — Specific Listing for Hexahydrocannabinol, A Currently Controlled Schedule I Substance

The DEA is giving hexahydrocannabinol (HHC) its own official spot on the Schedule I drug list starting May 4, 2026. This means HHC, a synthetic cousin of THC, is clearly controlled as a hallucinogen with a unique code, making rules easier to follow. Anyone making, selling, or using HHC should know it’s officially regulated now, but no new fees or costs are added.

2026-08517 — Schedules of Controlled Substances: Placement of 4F-MDMB-BUTICA, ADB-4en-PINACA, 5F-EDMB-PICA, and MMB-FUBICA in Schedule I

Starting May 1, 2026, the DEA officially puts four tricky chemicals—4F-MDMB-BUTICA, ADB-4en-PINACA, 5F-EDMB-PICA, and MMB-FUBICA—into Schedule I, meaning they’re now illegal to make, sell, or use without special permission. This affects anyone handling these substances, who will face strict rules and possible penalties. The move helps keep dangerous synthetic drugs off the streets and protects public health.

2026-08176 — Schedules of Controlled Substances: Rescheduling of Food and Drug Administration Approved Products Containing Marijuana From Schedule I to Schedule III; Corresponding Change to Permit Requirements

Starting April 28, 2026, FDA-approved marijuana-based medicines move from the strictest drug category (Schedule I) to a less strict one (Schedule III). This change helps medical marijuana businesses get faster federal permits to make and sell these products legally. Patients and companies benefit from easier access and clearer rules, while the government keeps control to meet international drug laws.

2026-08177 — Schedules of Controlled Substances: Rescheduling of Marijuana

The DEA is planning to move marijuana to Schedule III, which means it’s seen as less risky and easier to access legally. This change affects anyone using, selling, or researching marijuana and kicks off with a public hearing starting June 29, 2026. If you want to join the conversation, you need to sign up by May 28, 2026, so get ready for some big shifts in marijuana rules and opportunities!

Previous: 2026-06260 — Importer of Controlled Substances Application: Sterling Wisconsin, LLC

Sterling Wisconsin, LLC wants to become an official importer of a special controlled substance called 5-Methoxy-N,N-dimethyltryptamine. People who make or import similar drugs can share their thoughts or ask for a hearing by May 1, 2026. This move could shake up the drug import scene and means Sterling is stepping into a big new role soon.

Next: 2026-06263 — Foreign-Trade Zone (FTZ) 266, Notification of Proposed Production Activity; Tekni-Plex Flexibles, LLC; (Coated Nonwoven Materials for Healthcare Applications); Madison, Wisconsin

Tekni-Plex Flexibles, LLC in Madison, Wisconsin wants to start making special coated materials used in healthcare inside Foreign-Trade Zone 266. This means they can bring in certain foreign materials with lower or no import taxes to make products like cold seal films and coated papers. The change could save the company money on duties and help speed up production starting soon after approval.