EPA Quietly Logs New Chemicals for Routine Review
Published Date: 6/5/2026
Notice
Summary
The EPA is sharing updates on new chemicals submitted for review between November 2025 and January 2026. Companies making or importing these chemicals must follow new rules and can comment by July 6, 2026. This helps keep everyone safe while allowing innovation, with no new fees but important deadlines to watch.
Analyzed Economic Effects
5 provisions identified: 3 benefits, 2 costs, 0 mixed.
You must file a PMN/SNUN/MCAN first
If you plan to manufacture or import a new chemical substance for a non-exempt commercial purpose, TSCA section 5 requires you to submit a Premanufacture Notice (PMN), Microbial Commercial Activity Notice (MCAN), or Significant New Use Notice (SNUN) to EPA before starting the activity.
Test marketing exemption (TME) option exists
Under TSCA section 5(h)(1), you may apply for a test marketing exemption (TME) to manufacture or process a new chemical or a chemical subject to a Significant New Use Rule for test marketing if you show the activity will not present an unreasonable risk; EPA may allow manufacture under appropriate restrictions.
Microbial biotech follow 40 CFR part 725 rules
If you make or import new microbial products of biotechnology, premanufacture notification procedures are established in 40 CFR part 725. This includes MCANs and biotechnology exemptions (TERAs), TMEs for microorganisms, and Tier I and Tier II exemptions which you must follow.
Public comment deadline: July 6, 2026
You can submit comments on the new chemical submissions listed in this notice by July 6, 2026 through Regulations.gov using docket EPA-HQ-OPPT-2026-1387. Follow the online instructions and do not submit Confidential Business Information (CBI) via Regulations.gov.
EPA posts status and non-CBI data online
EPA provides status reports and non-confidential information on TSCA section 5 submissions online; you can view case details and non-CBI new chemical submissions at EPA's new-chemicals status page and in ChemView at https://chemview.epa.gov/chemview.
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