S1838119th CongressWALLET

DeOndra Dixon INCLUDE Project Act of 2025

Sponsored By: Senator John Hickenlooper

Introduced

Summary

Would create the INCLUDE Project, a federally coordinated research and training program focused on Down syndrome and its co-occurring conditions across the lifespan. It would support basic science, grow clinical trials that include or target people with Down syndrome, and push for biomarkers and treatments to improve daily functioning and health outcomes.

Show full summary
  • Families and people with Down syndrome would see research aimed at improving quality of life and treating common co-occurring conditions such as congenital heart disease, autoimmune disorders, and Alzheimer's disease. The bill notes about 6,000 U.S. births per year and a life expectancy now near 60 years.
  • Researchers would receive funding and technical assistance for high-risk, high-reward studies, creation of large study populations, and clinical trials expressly for or inclusive of people with Down syndrome.
  • The National Institutes of Health would coordinate related activities across its institutes, avoid duplicative work, and provide biennial reports to Congress cataloging supported research and any real-world clinical evidence.

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Bill Overview

Analyzed Economic Effects

1 provisions identified: 1 benefits, 0 costs, 0 mixed.

More NIH Research on Down Syndrome

If enacted, the bill would create the INCLUDE Project, a new NIH program to study Down syndrome. NIH would run the program directly or fund grants and contracts. The project would fund basic, clinical, and translational research, build a large diverse study cohort, and expand clinical trials that include people with Down syndrome. It would study chromosome 21 effects, biomarkers, co-occurring conditions like Alzheimer’s, and ways to improve daily living. NIH would coordinate work across its institutes, give technical help to grantees, and send Congress a cataloging report every two years. The bill does not set funding amounts and would not change taxes or federal benefit eligibility.

Sponsors & CoSponsors

Sponsor

John Hickenlooper

CO • D

Cosponsors

  • Markwayne Mullin

    OK • R

    Sponsored 5/21/2025

  • Sen. Bennet, Michael F. [D-CO]

    CO • D

    Sponsored 7/28/2025

  • Sen. Padilla, Alex [D-CA]

    CA • D

    Sponsored 9/16/2025

  • Shelley Capito

    WV • R

    Sponsored 9/16/2025

  • Sen. Coons, Christopher A. [D-DE]

    DE • D

    Sponsored 10/8/2025

  • Sen. Van Hollen, Chris [D-MD]

    MD • D

    Sponsored 10/8/2025

  • Sen. Moran, Jerry [R-KS]

    KS • R

    Sponsored 5/21/2025

  • Sen. Booker, Cory A. [D-NJ]

    NJ • D

    Sponsored 5/21/2025

Roll Call Votes

No roll call votes available for this bill.

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