South Dakota Administrative Code

Rule 20:51:05:10 Repealed. 20:51:05:10. Limitation on sale of drugs to persons under 16 years of age. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, SL 2012, ch 194, § 17, effective July 1, 2012.

Rule 20:51:05:11 Repealed. 20:51:05:11. Verbal warning required on sale of potent drugs. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, 2012, ch 194, § 18, effective July 1, 2012.

Rule 20:51:05:12 Repealed. 20:51:05:12. Advertising for mail order sale of drugs prohibited.Repealed. Source: SL 1975, ch 16, § 1; repealed, 6 SDR 103, effective May 5, 1980.

Rule 20:51:05:13 Repealed. 20:51:05:13. Advertising of price or discounts of drugs prohibited.Repealed. Source: SL 1975, ch 16, § 1; repealed, 3 SDR 45, effective December 18, 1976.

20:51:05:14. No advertising permitted on prescription blanks furnished to doctors. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 50 SDR 138, effective June 2, 2024.

20:51:05:15. Prescription required to dispense a drug. A pharmacist may dispense a drug only pursuant to a valid prescription issued by a licensed prescriber. The prescription must contain: (1) The full first and last legal name and address of the patient; (2) The drug name, stre…

20:51:05:15.01. Identification required for controlled drug prescription. Except for inpatients in a health care facility licensed pursuant to SDCL chapter 34-12, the pharmacy must have a policy to verify the identity of anyone attempting to purchase or pick up a prescription for…

20:51:05:15.02. Delivery of a prescription -- Signature required. A prescription may be delivered to a pharmacist by the following methods if permitted by law: (1) In writing; (2) Via facsimile; (3) Verbally; or (4) Electronically. A pharmacist or certified pharmacy intern shall …

20:51:05:15.03. Refilling of a prescription -- Requirements -- Controlled and noncontrolled drugs. A prescription may not be refilled except as designated on the original prescription or as subsequently authorized by the prescriber. Each refill must be entered on the back of the …

20:51:05:16. Prescription for Schedule II controlled drug requires date and signature of prescriber -- Not refillable. Repealed. Source: SL 1975, ch 16, § 1; transferred from § 20:51:05:02, 8 SDR 101, effective February 28, 1982; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 26…

Rule 20:51:05:17 Oral prescription permitted for Schedule II controlled drug in emergency. 20:51:05:17. Oral prescription permitted for Schedule II controlled drug in emergency. A pharmacist may in an emergency as defined in SDCL 22-42-2.2 dispense a Schedule II controlled drug p…

20:51:05:18. Partial filling of prescription for Schedule II controlled drug. Repealed. Source: 8 SDR 101, effective February 28, 1982; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 26 SDR 92, effective January 6, 2000; 50 SDR 138, effective June 2, 2024; 53 SDR 13, effective A…

20:51:05:19. Prescription required to dispense Schedule III or IV controlled drug -- Refill restricted. Repealed. Source: 8 SDR 101, effective February 28, 1982; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 26 SDR 92, effective January 6, 2000; 40 SDR 40, effective September 1…

20:51:05:20. Legend drug to be dispensed by prescription only -- Refill restricted. Repealed. Source: SL 1975, ch 16, § 1; transferred from §§ 20:51:05:06 and 20:51:05:07, 8 SDR 101, effective February 28, 1982; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 26 SDR 92, effective…

20:51:05:21. Labeling of prescription container for controlled or noncontrolled legend drug. A pharmacist filling a prescription for a controlled or noncontrolled legend drug shall attach to each container a label comprising: (1) The date dispensed; (2) The name, address, and tel…

20:51:05:22. Distribution of drugs to prescribers or pharmacies. A licensed pharmacy may distribute up to five percent of its controlled drugs and legend drugs to a prescriber licensed to prescribe, dispense, or distribute the drugs in the course of professional practice or to ot…

Rule 20:51:05:23 Distribution of dialysate or dialysis devices by the manufacturer or manufacturer's agent to a patient - Exempt from pharmacy licensure. 20:51:05:23. Distribution of dialysate or dialysis devices by the manufacturer or manufacturer's agent to a patient - Exempt f…

20:51:06:01. Application for pharmacy license -- Annual renewal required. A pharmacist operating a pharmacy in this state shall apply, on forms provided by the board, each year to the board for a license to operate the pharmacy. The fee for initial licensure is two hundred dollar…

20:51:06:02. Ownership or control by pharmacist required. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 50 SDR 138, effective June 2, 2024; 53 SDR 13, effective August 16, 2026. 20:51:06:02.01. Pharmacist-in-charge -- Duties. An applicatio…

20:51:06:02.01. Pharmacist-in-charge -- Duties. An application for a license to conduct a pharmacy as specified in § 20:51:06:02 must indicate the pharmacist-in-charge, as defined in SDCL 36-11-2. The pharmacist-in-charge must: (1) Be employed or under contract for pharmacy servi…

20:51:06:03. Application for opening a new pharmacy. An application for a license to operate a new pharmacy within South Dakota must be filed with the board at least thirty days before the pharmacy's opening date. The board may inspect the pharmacy prior to the opening date. Sour…

20:51:06:04. Grounds for suspending or revoking. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 50 SDR 138, effective June 2, 2024; 52 SDR 27, effective September 15, 2025; 53 SDR 13, effective August 16, 2026.

20:51:06:05. Must be registered in order to advertise pharmacy name. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 50 SDR 138, effective June 2, 2024.

20:51:06:06. Transfer of pharmacy registration. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 50 SDR 138, effective June 2, 2024.

20:51:06:07. Changes in ownership or location reported to the board--Patients notified of closure of pharmacy. A change in the location, ownership, or name of a pharmacy, or the closure of business as a pharmacy, must be reported to the board at least ten days prior to the change…

20:51:06:08. Valid permit must be displayed. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 52 SDR 27, effective September 15, 2025.

20:51:06:09. Permit expires one hundred twenty days after death of pharmacist owner. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 50 SDR 138, effective June 2, 2024; 52 SDR 27, effective September 15, 2025; 53 SDR 13, effective August 16,…

20:51:06:10. Provisions for pharmacist temporary absence from pharmacy. Where the premises includes a licensed pharmacy and a general merchandise area, it is not a violation of SDCL chapter 36-11 if public entrances to the general merchandise area are kept open for business witho…

20:51:06:11. Pharmacy requirements for nonpharmacist owners. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 26 SDR 92, effective January 6, 2000; 50 SDR 138, effective June 2, 2024.

20:51:06:12. Pharmacy requirements for pharmacist owners. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 26 SDR 92, effective January 6, 2000; 50 SDR 138, effective June 2, 2024.

Rule 20:51:06:13 Repealed.. 20:51:06:13. Display of nonprescription drugs in pharmacy. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 86, effective November 27, 1985; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 24 SDR 160, effective May 26, 1998; repealed, SL 2012, ch 194, § 1…

20:51:07:01. Pharmacy must comply with all public health regulations. A pharmacy must comply with all public health regulations regarding sanitation and is subject to South Dakota Board of Pharmacy inspections. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1…

Rule 20:51:07:02 Repealed. 20:51:07:02. Publications required.Repealed. Source: SL 1975, ch 16, § 1; 2 SDR 21, effective September 23, 1975; 6 SDR 103, effective May 5, 1980; 11 SDR 92, effective January 16, 1985; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, 14 SDR 1…

20:51:07:03. Minimum equipment requirements. A pharmacy owner must make available and maintain all equipment needed to provide pharmacy services for the location, as determined by the pharmacist-in-charge. Any equipment that requires certification, maintenance, or calibration mus…

20:51:07:04. Publication and reference library. All pharmacy staff must have access to South Dakota pharmacy laws and rules, federal laws and rules, all governing or regulatory agency documents needed to conduct pharmacy services, and the telephone number of the nearest poison co…

20:51:08:01. Segregated sales display required. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, SL 2012, ch 194, § 20, effective July 1, 2012.

Rule 20:51:08:02 Repealed. 20:51:08:02. Display of drugs or poisons with general merchandise prohibited. Repealed. Source: SL 1975, ch 16, § 1; repealed, 12 SDR 86, effective November 27, 1985.

20:51:08:03. No drug or poison can be displayed where buyer can pick up unless in restricted drug area. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, SL 2012, ch 194, § 21, effective July 1, 2012.

20:51:08:04. Only pharmacists and persons over 16 can make sales from restricted drug area. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, SL 2012, ch 194, § 22, effective July 1, 2012.

20:51:08:05. Requirements of sale from restricted drug area. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, SL 2012, ch 194, § 23, effective July 1, 2012.

Rule 20:51:08:06 Repealed. 20:51:08:06. Requirements for the sale of items from the restricted drug area. Repealed. Source: SL 1975, ch 16, § 1; 6 SDR 103, effective May 5, 1980; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, SL 2012, ch 194, § 24, effective July 1, 20…

20:51:08:07. Restricted drug areas must be under supervision of pharmacist. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, SL 2012, ch 194, § 25, effective July 1, 2012.

Rule 20:51:08:08 Repealed. 20:51:08:08. Pharmacist responsible to public for every act of selling. Repealed. Source: SL 1975, ch 16, § 1; repealed, 12 SDR 86, effective November 27, 1985.

Rule 20:51:08:09 Repealed. 20:51:08:09. Self-service signs prohibited. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, SL 2012, ch 194, § 26, effective July 1, 2012.

Rule 20:51:09:01 Repealed. 20:51:09:01. Application. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 24 SDR 160, effective May 26, 1998; repealed, SL 2012, ch 194, § 27, effective July 1, 2012.

Rule 20:51:09:02 Repealed. 20:51:09:02. Examination.Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; repealed, 24 SDR 160, effective May 26, 1998.

Rule 20:51:09:03 Repealed. 20:51:09:03. Original package sales only. Repealed. Source: SL 1975, ch 16, § 1; 12 SDR 151, 12 SDR 155, effective July 1, 1986; 24 SDR 160, effective May 26, 1998; repealed, SL 2012, ch 194, § 28, effective July 1, 2012.