Producer

Pfizer Inc. (Hospital Division)

HQ US · New Yorkwebsite ↗

Pfizer's Hospital Division (formerly Pfizer Injectables/Hospira) manufactures pharmaceutical fentanyl citrate injection and fentanyl transdermal system products. Pfizer/Hospira's McPherson KS facility is a key US site for injectable controlled substances. Pfizer holds significant DEA quotas for pharmaceutical fentanyl manufacturing and is a primary supplier to US hospital systems. Pfizer's fentanyl products are essential for anesthesiology and critical care medicine.

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  • Fentanyl Injectables & Patches

    45%
  • Anesthesia Products

    30%
  • Other Hospital Controlled Substances

    25%

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  • Did you know2022

    Pharmaceutical fentanyl (Pfizer Hospital) is used in operating rooms as a surgical anesthetic adjunct and in cancer pain management — a legitimate medical supply chain with DEA Schedule II controls. The illicit fentanyl that is killing ~70,000 Americans annually is synthetically produced in Mexico (using Chinese precursors) and bears no connection to pharmaceutical manufacturing. However, the regulatory and political response to the illicit fentanyl crisis directly constrains pharmaceutical fentanyl supply: hospitals have faced shortages of surgical fentanyl because DEA manufacturing quotas are set without distinguishing between therapeutic use trajectories and diversion risk. The illicit drug crisis supply chain and the hospital surgery supply chain share DEA regulatory constraints, creating surgical anesthesia drug shortages as a collateral effect of illicit opioid policy.

    ASHP
  • Origin2023

    Pfizer's fentanyl products trace primarily to the 2009 acquisition of Wyeth, which had previously acquired Warner-Lambert's Duragesic (fentanyl transdermal patch) franchise. Duragesic was originally developed by Janssen Pharmaceutica (now Johnson & Johnson) — fentanyl was synthesized by Paul Janssen in Belgium in 1960, one of the most potent opioids ever made. Pfizer/Hospira's McPherson, Kansas manufacturing site expanded its fentanyl injectable capacity significantly as hospital surgical procedures grew in the 2000s-2010s, making it the primary US domestic manufacturer of pharmaceutical fentanyl for anesthesia. Simultaneously, illicit fentanyl from Chinese and Mexican manufacturers devastated communities, creating the backdrop against which all pharmaceutical fentanyl supply chain decisions are now made.

    Pfizer Inc