Producer
Shanxi Fenge Pharmaceutical Co., Ltd.
Chinese pharmaceutical API manufacturer based in Shanxi province; significant producer of camptothecin API and related semi-synthetic intermediates. Shanxi Fenge processes camptothecin extracted from Camptotheca acuminata plant material sourced from cultivation regions (principally Guangxi, Fujian, and Jiangsu) and converts it to pharmaceutical-grade camptothecin powder used as a starting material for irinotecan and topotecan semi-synthesis. The company holds Chinese GMP certification and supplies API to Chinese generic drug manufacturers and international pharmaceutical buyers.
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2 facilities
Fujian & Jiangsu Camptotheca acuminata Cultivation Zones →
CNFujian · cultivation
Secondary Camptotheca acuminata cultivation zones in Fujian, Jiangsu, and Shandong provinces of China. Fujian's subtropical coast and Jiangsu's temperate zones support C. acuminata cultivation at different altitude and temperature profiles than Guangxi, providing geographic diversification of the botanical supply within China. Fujian plantation biomass is processed by regional extraction companies and sold as camptothecin extract powder to API manufacturers including Shanxi Fenge. Shandong cultivation (cooler northern climate) tends to yield lower alkaloid concentrations but higher biomass. Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609381/
Shanxi Fenge Pharmaceutical API Manufacturing Plant →
CNShanxi · manufacturing
Shanxi Fenge Pharmaceutical's API manufacturing facility in Shanxi province. The plant processes camptothecin extract powder into pharmaceutical-grade camptothecin API using solvent extraction, crystallization, and chromatographic purification methods. Chinese GMP-certified; supplies domestic and export markets. The Shanxi location is logistically central within China but geographically distant from the Guangxi cultivation zones, representing a two-step supply chain: plant material from south China (Guangxi/Fujian) → API purification in north-central China (Shanxi) → semi-synthesis to irinotecan in China or India.
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Camptothecin & 10-HCPT API
70%Semi-Synthesis CPT Derivatives
20%Other Pharmaceutical APIs
10%
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Did you know2012
Shanxi Fenge produces camptothecin API that goes into irinotecan (CPT-11) — used for colon cancer — and topotecan — used for ovarian and lung cancer. Both are topoisomerase I inhibitors. The same camptothecin chemistry that is the precursor for cancer treatment is also the basis for anti-HIV research and agricultural pesticide research (camptothecin analogues show insecticidal activity). While Shanxi Fenge primarily serves the pharmaceutical market, the chemical intermediates they produce sit at the intersection of oncology drugs, antiviral research, and potential agricultural chemistry — a chemical family where the cancer drug precursor and the potential pesticide active share the same Chinese extraction and semi-synthesis infrastructure.
PMC ↗Origin2023
Shanxi Fenge Pharmaceutical is based in Shanxi Province — historically China's coal mining heartland and the origin of the famous Shanxi merchant (Jin merchants) banking tradition that dominated Chinese commerce from the 14th to early 20th centuries. The province's modern pharmaceutical sector grew alongside its coal-chemical industry, applying extraction and chemical processing capabilities (developed for coal chemistry) to pharmaceutical API production. Shanxi Fenge sources Camptotheca acuminata botanical material from growing regions in Guangxi and Sichuan for its camptothecin extraction, then semi-synthesizes CPT derivatives for global oncology drug manufacturers.
Shanxi Fenge Pharmaceutical ↗