Producer

SI Group (Exited ibuprofen market September 2024)

American specialty chemicals company (HQ Schenectady NY; private equity owned, formerly Schenectady International); was the last significant non-Asian, non-IOL Chemicals ibuprofen API producer outside China — until announcing its exit from the ibuprofen API market in September 2024. SI Group's exit eliminated the last meaningful Western ibuprofen API production capability, leaving IOL Chemicals (India) as the only significant non-Chinese global ibuprofen producer. SI Group cited Chinese competitive pricing as the primary reason for exit — the same competitive dynamic that eliminated US and European APAP (acetaminophen) API production had finally consumed the last Western ibuprofen API producer. SI Group's exit in September 2024 is included in this record as a historical marker of the Western pharmaceutical API manufacturing withdrawal from ibuprofen.