pharmaceutical · input
Synthetic steroid hormones; primary treatment for eczema, psoriasis, contact dermatitis; >70% of API supply manufactured in India and China from plant sterol precursors; clobetasol propionate is the highest-potency class I corticosteroid
5
Source countries
6
Companies
1
Goods affected
0
Claims on record
What depends on it
1 essential American goods rely on corticosteroid apis (betamethasone, clobetasol, triamcinolone) somewhere upstream in their supply chain.
Where it comes from
Share of global supply, by country.
| Country | Share of supply |
|---|---|
| INIndia | 45% |
| CNChina | 28% |
| ILIsrael | 12% |
| ITItaly | 5% |
| USUnited States | 3% |
Who makes it
6 companies produce corticosteroid apis (betamethasone, clobetasol, triamcinolone).
One of the world's largest manufacturers of generic topical dermatology products; ~40% market share in US generic corticosteroid creams and ointments; owned by Sun Pharmaceutical Industries (India); manufactures in Israel, Canada, and US; controls a significant share of the US generic topical market for high-potency steroids.
Major Indian pharmaceutical company with significant US generic topical dermatology business; one of the top 5 US market share holders in prescription topical steroids; also develops novel dermatology molecules; manufactures corticosteroid and antifungal APIs and finished products for US/EU markets.
Indian pharmaceutical API manufacturer (NSE: DIVISLAB, HQ Hyderabad; ~₹75B revenue); one of India's largest and most technically sophisticated pharmaceutical API producers, specializing in complex APIs including fluoroquinolones (ciprofloxacin, ofloxacin, levofloxacin), carotenoids (nutraceuticals), and custom synthesis for branded pharmaceutical companies. Divi's Laboratories has never been involved in a major USFDA warning letter or import alert (unusual for an Indian API company of its scale) — maintaining essentially clean regulatory compliance across its multiple Visakhapatnam, Andhra Pradesh production facilities. Divi's produces fluoroquinolone APIs including ciprofloxacin HCl for ophthalmic applications for global generic pharmaceutical customers. Divi's is also one of India's most consistently profitable pharmaceutical companies — its focus on volume API production at high quality has created a near-uninterruptible supply chain position across multiple essential medicines.
Major Chinese steroidal API producer; one of China's largest pharmaceutical companies by API volume. Produces corticosteroid intermediates and finished APIs (betamethasone valerate, triamcinolone acetonide, and others) from phytosterol precursors (primarily from soybean processing). Listed on Shenzhen Stock Exchange. Also produces analgesics and antipyretics.
Italian specialty corticosteroid API manufacturer; one of few European producers of pharmaceutical-grade corticosteroid bulk actives (betamethasone, triamcinolone, clobetasol, fluocinolone). Serves as alternative non-Asian source for European regulated markets. Part of Zambon Group. European regulatory compliance (EU GMP) provides competitive advantage for EU-based pharmaceutical companies sourcing corticosteroid APIs.
