chemical · input

HFA-227ea Propellant (Apaflurane)

1,1,1,2,3,3,3-heptafluoropropane; HFA propellant used in some pMDIs (GSK fluticasone products, AstraZeneca Pulmicort pMDI). GWP of 3,350 — the highest-GWP pMDI propellant; subject to accelerated phase-out pressure. Also used in pharmaceutical-grade fire suppression (FM-200), creating industrial competition for supply.

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Source countries

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Companies

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Goods affected

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Claims on record

What depends on it

Goods that need this input

1 essential American goods rely on hfa-227ea propellant (apaflurane) somewhere upstream in their supply chain.

Who makes it

Supplier companies

1 company produce hfa-227ea propellant (apaflurane).

Koura (Orbia Fluor & Energy Materials)(ORBIA)

HQ MX60% share

Division of Orbia (formerly Mexichem). World leader in pharmaceutical-grade HFA propellants under the Zephex brand. Zephex 134a in ~75% of global pMDIs. Only FDA-registered active HFA-134a supplier in the US. Opened world's first commercial HFA-152a pharmaceutical manufacturing facility at Runcorn, UK in March 2022.