chemical · input

m-Cresol (Metacresol)

Antimicrobial preservative (2.3–3.2 mg/mL) in insulin formulations that also stabilizes the insulin crystal structure. Derived from coal tar distillation; commodity chemical. Multiple manufacturers globally; not a supply constraint.

4

Source countries

4

Companies

1

Goods affected

0

Claims on record

What depends on it

Goods that need this input

1 essential American goods rely on m-cresol (metacresol) somewhere upstream in their supply chain.

Where it comes from

Source countries

Share of global supply, by country.

Who makes it

Supplier companies

4 companies produce m-cresol (metacresol).

Koppers Holdings Inc.

HQ US

Largest provider of creosote-treated railroad crossties to North American Class I railroads (~35% market share); operates 9+ pressure treatment facilities nationally. Owns the creosote supply chain through KMG Chemicals acquisition — controls coal tar distillation (converting steel mill coal tar byproduct into creosote oil) AND the treatment plants that pressure-impregnate hardwood ties. Entered long-term coal tar supply agreements with ArcelorMittal USA (3 coke plants) through 2026 to stabilize creosote supply. Koppers is also a major supplier of carbon pitch and naphthalene for aluminum smelting anodes — the same coal tar chemistry that preserves railroad ties also enables aluminum smelting. As integrated steel mills (using coke ovens) decline and electric arc furnaces grow, Koppers faces a structural long-term coal tar supply contraction.

Lanxess AG

HQ DE

Specialty chemicals major; significant Western producer of phosphorus trichloride (PCl3) and other phosphorus-based chemicals.

Rain Carbon (Rain Industries)(RAIN.NS)

HQ IN

Leading global petcoke trading intermediary and calciner; Rain CII Carbon (US subsidiary) is the largest single recipient of Indian GPC import quotas (462,589t in FY2025-26); operates calciners in US, India, Belgium, and Russia; sources green petcoke from Gulf Coast refineries.

Sasol(SSL)

HQ ZA

South African integrated energy and chemicals company (JSE/NYSE-listed); unique in the LAB market for using Fischer-Tropsch (FT) wax cracking to produce its own normal paraffins (NP) — the LAB feedstock — rather than sourcing from oil refineries. Sasol operated LAB plants in Lake Charles, Louisiana (USA) and Augusta, Sicily (Italy); both were mothballed in Q2-Q3 2025 due to 'decline in competitiveness due to energy costs in Europe and market oversupply.' Also produces synthetic fuels, commodity chemicals, and specialty chemicals from coal- and gas-based FT processes in South Africa.