chemical · input

Para-aminophenol (PAP) — APAP precursor

Direct chemical precursor for acetaminophen synthesis. China produces >75% of global PAP and supplies 60-80% of India's PAP requirements, meaning India's 26% APAP share is itself substantially China-dependent.

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Source countries

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Companies

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Goods affected

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Claims on record

What depends on it

Goods that need this input

1 essential American goods rely on para-aminophenol (pap) — apap precursor somewhere upstream in their supply chain.

Where it comes from

Source countries

Share of global supply, by country.

CountryShare of supply
CNChina78%
INIndia12%
EUEuropean Union8%

Who makes it

Supplier companies

2 companies produce para-aminophenol (pap) — apap precursor.

Anqiu Lu'an Pharmaceutical

HQ CN22% share

World's largest single-site APAP (acetaminophen) API manufacturer; ~40,000–50,000 tonnes/year capacity; produces ~35% of Chinese APAP output; FDA DMF filed 2011. Also produces para-aminophenol (PAP) as an upstream integrated producer.

Hebei Jiheng Pharmaceutical Co., Ltd.

HQ CN18% share

Chinese pharmaceutical and chemical company (SZSE: 002216, HQ Hengshui, Hebei; ~RMB 5B revenue); major producer of acetaminophen (paracetamol) API and its key precursor para-aminophenol (PAP). Hebei Jiheng is one of China's largest single-facility APAP producers and a major PAP manufacturer — controlling the full supply chain from aniline (derived from benzene/toluene/xylene petrochemicals) through PAP to APAP. Hebei province's chemical industry cluster (Hengshui, Shijiazhuang) includes multiple facilities producing the aniline, nitrobenzene, and para-aminophenol intermediates that feed APAP synthesis globally. Hebei Jiheng's PAP production capability makes it a critical upstream supplier not just for its own APAP but for Indian APAP producers (Farmson, Granules) who depend on Chinese PAP when domestic Indian PAP capacity is insufficient.