Fluoride Actives (NaF / SMFP) for Toothpaste

China's largest fluorochemicals conglomerate; headquartered in Hangzhou; primary production base in Quzhou, Zhejiang Province. Also has bases in Ningbo, Zhoushan, Zhuji (Zhejiang) and Jiangsu. Export arm: Xiamen Juda Chemical & Equipment Co. (Siming District, Xiamen, Fujian — focused on fluorinated chemical exports including HFC-227ea). Product lines include HFC-227ea (fire suppression grade) among seven major fluorinated chemical series. FDA DMF, UL, CE, DOT, KGS, ASME, ISO, OHSAS certified. 2012: signed cooperation agreement with Honeywell in Quzhou for HFC-125 production to feed Honeywell's R-410A blends — confirming Juhua's role as supply partner for major Western companies. China's largest fluorochemicals production base and primary source of cost-competitive HFC-227ea for Asian and global markets. State-owned enterprise (Zhejiang Juhua Group Corporation).

Baiyin Non-Ferrous Group is a large Chinese state-affiliated enterprise headquartered in Baiyin City, Gansu Province — China's primary fluorspar-mining and fluoride-processing region. Baiyin operates integrated fluorspar mining, HF production, and downstream fluoride compound manufacturing (NaF, MFP, aluminum fluoride, ammonium bifluoride). Gansu Province hosts some of China's highest-grade fluorspar (acidspar) deposits, giving Baiyin a low-cost feedstock advantage. Baiyin fluoride compounds are exported globally, including to consumer goods manufacturers seeking lower-cost fluoride actives. China overall produces ~60-65% of global fluoride compounds by volume, with Gansu and Hunan provinces as the primary production centres.

Mexican diversified industrial company (BMV: ORBIA, HQ Mexico City; ~$8.5B revenue); Koura division (formerly Mexichem Fluor) is the world's largest fluorspar and HF producer by volume, with fluorspar mines in Mexico (San Luis Potosi state) and HF production plants in Mexico (Pajaritos, Veracruz), the UK (Runcorn), and elsewhere. Mexico's fluorspar reserves (acid-grade fluorite, CaF2) — among the world's largest, concentrated in San Luis Potosi and Durango states — feed Koura's HF production, making it uniquely vertically integrated from mine to HF. Mexico is the world's largest fluorspar exporter (~25% of global supply), and Koura controls a significant fraction of that production. Orbia is also a major PVC pipe (Amanco brand) and precision irrigation company — a diversified conglomerate where HF chemistry sits alongside water infrastructure.

Honeywell (NASDAQ: HON) operates one of the largest hydrogen fluoride (HF) production complexes in North America at Geismar, Louisiana — a 1,500-acre petrochemical site in Ascension Parish. HF is the precursor to essentially all fluoride compounds used in toothpaste actives (NaF, MFP, SnF2). Honeywell Specialty Materials produces high-purity NaF, potassium fluoride, and fluorochemical intermediates sold to pharma, personal care, and semiconductor customers. The Geismar site processes fluorspar from multiple global sources and is rated for several hundred thousand tonnes of HF annually. Honeywell is also a major supplier of specialty fluorine chemicals to the electronics sector (wafer etching, semiconductor cleaning).

Orbia (formerly Mexichem, NYSE: ORC) is a Mexican specialty chemical and polymer conglomerate whose Fluor segment (Mexichem Fluor) is one of the largest hydrofluoric acid (HF) producers in the Americas. The company mines fluorspar at its San Luis Potosí operations and converts it to anhydrous HF and downstream fluoride compounds including sodium fluoride (NaF) for industrial and personal care uses. Mexichem Fluor UK (Runcorn, Cheshire, England — former ICI/Ineos Fluor site) is the primary EU/UK-facing NaF production facility. Orbia Fluor also produces refrigerant fluorocarbons (HFC/HFO). Together Mexichem Fluor UK and San Luis Potosí make Orbia one of the top three non-Chinese producers of fluoride compounds.

Syensqo is the specialty chemicals company spun out of Solvay in late 2023. Solvay's Fluorine Chemistry business — now within Syensqo — produces pharmaceutical- and personal-care-grade sodium fluoride, potassium fluoride, and fluoride intermediates at its Panoli facility in Gujarat, India (Bharuch district). Panoli is one of the few ISO-certified, pharmaceutical-grade NaF production sites outside China, making Syensqo a key supplier to multinational toothpaste manufacturers requiring high-purity certified fluoride actives. Syensqo also produces advanced PVDF fluoropolymers and specialty fluorinated solvents — a highly diversified fluorine chemistry portfolio.

ICF (Industrias Químicas del Flúor S.A.) is a Spanish specialty fluorine chemical company headquartered in Barcelona. ICF produces sodium fluoride (NaF), sodium monofluorophosphate (MFP), potassium fluoride, and aluminum fluoride at its manufacturing site in Tarragona (Catalonia). ICF is a significant supplier of MFP specifically — sodium monofluorophosphate for oral care — and is one of very few non-Chinese producers of MFP outside of multinationals like Solvay/Syensqo. ICF supplies European toothpaste manufacturers directly, providing an EU-based alternative to Chinese MFP sources. MFP is used in classic fluoride toothpastes (Aquafresh, Sensodyne, many store-brands).

Belgian phosphate chemicals company with 140+ years of history (1882) and 1,400 employees. Produces purified phosphoric acids, phosphate salts (including food-grade STPP), and fluorine products at sites in Belgium, France, USA, and Switzerland. Prayon's wet-process phosphoric acid technology is used to produce over 50% of the world's merchant-grade phosphoric acid — making it the critical licensor of the key manufacturing technology behind the global phosphate supply chain. In August 2024, Prayon acquired Natural Enrichment Industries to strengthen its US footprint. Also a member of the European Sustainable Phosphorus Platform.