Grünenthal PRO
HQ DE45% share
pharmaceutical · input
Tapentadol API (Nucynta / Palexia)
Semi-synthetic opioid API with dual mechanism: mu-opioid receptor agonism + norepinephrine reuptake inhibition (NRI). Developed by Grünenthal; licensed to Janssen Pharmaceuticals (J&J) as Nucynta in the US and marketed as Palexia in EU/ROW. Tapentadol offers comparable analgesia to oxycodone with reportedly lower constipation and lower abuse potential. Schedule II in the US. Generic API market expanding post-patent; Grünenthal PRO is a primary API originator-supplier.
0
Source countries
3
Companies
1
Goods affected
0
Claims on record
What depends on it
Goods that need this input
1 essential American goods rely on tapentadol api (nucynta / palexia) somewhere upstream in their supply chain.
Who makes it
Supplier companies
3 companies produce tapentadol api (nucynta / palexia).
AMI Life Sciences Pvt Ltd
HQ IN
Indian API manufacturer (Vadodara, Gujarat) with documented tapentadol API exports (Q2 2024).
Molkem Chemicals Pvt Ltd
HQ IN
Indian fine-chemical / API maker with documented tapentadol API exports (Q2 2024).