pharmaceutical · input

Tramadol API

Synthetic opioid API for Schedule IV oral analgesics; Grünenthal PRO (Switzerland/Germany) is the originator and supplies approximately one-third of global tramadol API output.

3

Source countries

4

Companies

1

Goods affected

0

Claims on record

What depends on it

Goods that need this input

1 essential American goods rely on tramadol api somewhere upstream in their supply chain.

Where it comes from

Source countries

Share of global supply, by country.

CountryShare of supply
INIndia45%
CNChina30%
DEGermany18%

Who makes it

Supplier companies

4 companies produce tramadol api.

Grünenthal PRO

HQ DE33% share

Aarti Pharmalabs(543748.BO)

HQ IN

Indian API/intermediate maker; supplier of various pharmaceutical actives.

Dr. Reddy's Laboratories

HQ IN

Indian multinational pharmaceutical company (NSE: DRREDDY; HQ Hyderabad) with significant irinotecan API and finished dose manufacturing. Dr. Reddy's manufactures irinotecan hydrochloride injection for the U.S. and European generic markets — one of the leading generic irinotecan suppliers approved by FDA and EMA. The company converts camptothecin (procured primarily from Chinese botanical extraction sources) into irinotecan API via semi-synthesis at its Hyderabad API facilities. Dr. Reddy's broader oncology generics franchise includes paclitaxel, docetaxel, and topotecan, making it one of the few Indian companies with a full camptothecin-class API portfolio. Supply of irinotecan to the U.S. critical care oncology market is a significant part of the company's FDA-regulated generic pharmaceutical business.

Zydus Lifesciences (Cadila)(532321.BO)

HQ IN

Indian pharma; API + generic formulations incl. analgesics.