Origin

How a vaccine trap locked in poultry dependence

The Marek's disease vaccine, introduced in the 1970s, inadvertently created a self-reinforcing cycle that made the entire commercial poultry industry permanently reliant on vaccination.

The number

1970svaccine introduction

The vaccine allows infected birds to survive and shed virus, eliminating the natural selection pressure that would have culled more lethal strains. Within a decade, virulence evolved so dramatically that today's unvaccinated birds face ~100% mortality—a death rate that would have been impossible in the pre-vaccine era, when lethality was self-limiting.

Source: Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens · PLoS Biology · Jun 30, 2015

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