Title 42 › CHAPTER 23 — DEVELOPMENT AND CONTROL OF ATOMIC ENERGY › SUBCHAPTER IX — ATOMIC ENERGY LICENSES › § 2142
The Commission can only issue or change a license to let highly enriched uranium (HEU) be used as a target to make medical isotopes in a U.S. reactor if two things happen. First, the Commission must find there is no other target that can be used in that reactor, and the person getting the target must promise to switch to the alternative as soon as it becomes usable. Second, the Secretary of Energy must say the U.S. government is actively helping to develop such an alternative. Definitions: "Alternative medical isotope production target" = a reactor target with less than 20 percent U‑235. "Can be used" = the target is approved by the Department of Energy’s Reduced Enrichment Research and Test Reactor Program and would let most current and planned work and isotope production continue without a large rise in reactor operating costs. "Highly enriched uranium" = uranium with 20 percent or more U‑235. "Medical isotope" = materials like molybdenum‑99, iodine‑131, xenon‑133, and other radioactive substances used to make radiopharmaceuticals for diagnosis, treatment, or research.
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The Public Health and Welfare, Source: USLM XML via OLRC
Legislative History
Reference
Citation
42 U.S.C. § 2142
Title 42, The Public Health and Welfare
Last Updated
Aug 21, 2026
Release point: 119-102