Title 42, The Public Health and WelfareRelease 119-102

§285l–1 Applied Toxicological Research and Testing Program

Title 42 › CHAPTER 6A — PUBLIC HEALTH SERVICE › SUBCHAPTER III — NATIONAL RESEARCH INSTITUTES › Part C — Specific Provisions Respecting National Research Institutes › subpart 12 — national institute of environmental health sciences › § 285l–1

Last updated Aug 21, 2026|Official source

Summary

Create a program inside the Institute called the Applied Toxicological Research and Testing Program to do applied research and testing on toxicology. The Institute director must expand knowledge about how environmental agents affect health; collect more toxicology information on selected chemicals; develop and check tests and procedures, including alternative methods that can reduce or eliminate animal use in safety testing; set rules for approving alternative tests and recommend how validated alternatives can be accepted for regulatory use; share results with government, medical, scientific, and public audiences; and coordinate related work across the Department of Health and Human Services.

Full Legal Text

Title 42, §285l–1

The Public Health and Welfare, Source: USLM XML via OLRC

(a)There is established within the Institute a program for conducting applied research and testing regarding toxicology, which program shall be known as the Applied Toxicological Research and Testing Program.

(b)In carrying out the program established under subsection (a), the Director of the Institute shall, with respect to toxicology, carry out activities—

(1)to expand knowledge of the health effects of environmental agents;

(2)to broaden the spectrum of toxicology information that is obtained on selected chemicals;

(3)to develop and validate assays and protocols, including alternative methods that can reduce or eliminate the use of animals in acute or chronic safety testing;

(4)to establish criteria for the validation and regulatory acceptance of alternative testing and to recommend a process through which scientifically validated alternative methods can be accepted for regulatory use;

(5)to communicate the results of research to government agencies, to medical, scientific, and regulatory communities, and to the public; and

(6)to integrate related activities of the Department of Health and Human Services.

Reference

Citations & Metadata

Citation

42 U.S.C. § 285l–1

Title 42, The Public Health and Welfare

Last Updated

Aug 21, 2026

Release point: 119-102