2025-00743Notice

Teva Branded Pharmaceutical Products R&D, Inc., et al.; Withdrawal of Approval of 12 New Drug Applications

Published Date: 1/15/2025

Notice

Summary

The FDA is officially pulling the plug on 12 drug approvals because the companies stopped selling these medicines. This change kicks in on February 14, 2025, and it mainly affects the drug makers and anyone tracking these products. Don’t worry—companies can ask to bring these drugs back if they want to in the future!

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Analyzed Economic Effects

3 provisions identified: 1 benefits, 2 costs, 0 mixed.

FDA Withdraws 12 Drug Approvals

The FDA is withdrawing approval of 12 New Drug Applications (NDAs) as of February 14, 2025, because the applicants told FDA the products are no longer marketed and asked for withdrawal. The withdrawal applies to the entire listed applications (all strengths and forms) and is without prejudice to refiling if an applicant wants to seek approval again.

Selling These Drugs Without Approval Is Prohibited

After February 14, 2025, introducing or delivering for introduction into interstate commerce any of the listed products without an approved NDA will violate sections 505(a) and 301(d) of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 355(a) and 331(d)). Companies, distributors, or others who move these products across state lines must ensure an approved NDA is in place.

Existing Inventory Can Still Be Dispensed

Drug products listed in the withdrawn NDAs that are in inventory on February 14, 2025, may continue to be dispensed until those inventories are depleted or the products reach their expiration dates, or otherwise become violative, whichever occurs first. This allows current stock to be used after the approval withdrawal date rather than being immediately unusable.

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Key Dates

Published Date
Effective Date
1/15/2025
2/14/2025

Department and Agencies

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Independent Agency
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