2025-15432NoticeWallet

HRSA Debates Adding Rare MLD to Newborn Disease Screening Panel

Published Date: 8/14/2025

Notice

Summary

HRSA is thinking about adding Metachromatic Leukodystrophy (MLD), a serious condition, to the list of diseases newborns get screened for. This means babies could be tested early without families paying extra, helping catch MLD sooner and possibly save lives. HRSA wants your thoughts before making a final call, so speak up soon!

Analyzed Economic Effects

3 provisions identified: 2 benefits, 0 costs, 1 mixed.

If Added, Screening Covered Without Cost-Sharing

If HRSA adds Metachromatic Leukodystrophy (MLD) to the Recommended Uniform Screening Panel (RUSP), newborn screening for MLD that is included in HRSA-supported comprehensive guidelines must be covered by non-grandfathered health plans without cost-sharing (no co-payment or co-insurance).

Supports Early Newborn Screening for MLD

HRSA is considering recommending MLD be added to the RUSP to support screening during the newborn period and is specifically asking for evidence about the potential benefit of early screening and the availability of effective treatments for MLD.

State Screening Capacity Will Be Considered

HRSA will consider the ability of state newborn screening programs to screen for MLD when deciding whether to recommend adding MLD to the RUSP, so state program capacity is part of the decision process.

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Key Dates

Published Date
8/14/2025

Department and Agencies

Department
Independent Agency
Agency
Health and Human Services Department
Health Resources and Services Administration
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