2025-22683Notice

FDA Plays Marie Kondo With 20 Dead Generic Drugs

Published Date: 12/12/2025

Notice

Summary

The FDA is officially pulling the plug on 20 drug approvals because the companies, including Pfizer and Monarch Pharmaceuticals, told the FDA they stopped selling these medicines. This change kicks in on January 12, 2026, but companies can apply again if they want. No money penalties here—just a cleanup to keep the drug list fresh and accurate.

Analyzed Economic Effects

2 provisions identified: 1 benefits, 1 costs, 0 mixed.

Approval Withdrawn for 20 Drug ANDAs

The FDA is withdrawing approval of 20 abbreviated new drug applications (ANDAs) as of January 12, 2026. The notice lists specific products (for example, TAPAZOLE tablets, several NEOSPORIN formulations, Gentamicin sulfate injectables, ADRIAMYCIN PFS, Pancuronium Bromide, and others) whose approvals are withdrawn at that date.

Existing Inventory May Still Be Dispensed

Products listed in the withdrawal table that are in inventory on January 12, 2026 may continue to be dispensed until inventories are depleted, reach their expiration dates, or otherwise become violative, whichever occurs first. This allows existing stock to remain available to patients until those limits are reached.

Your PRIA Score

Score Hidden

Personalized for You

How does this regulation affect your finances?

Sign up for a PRIA Policy Scan to see your personalized alignment score for this federal register document and every other regulation we track. We analyze your financial profile against policy provisions to show you exactly what matters to your wallet.

Free to start

Key Dates

Published Date
Effective Date
12/12/2025
1/12/2026

Department and Agencies

Department
Independent Agency
Agency
Health and Human Services Department
Food and Drug Administration
Source: View HTML
Back to Federal Register

Take It Personal

Get Your Personalized Policy View

Start a Free Government Policy Watch to see how policy affects your household, then upgrade to PRIA Full Coverage for year-round monitoring.

Already have an account? Sign in