Replace Animal Tests Act of 2025

New rules for animal test data

If enacted, this bill would bar submission of animal-test data to FDA, EPA, USDA, or CPSC when the agency has accepted an alternative non-animal test method or has issued a waiver. It would allow animal data in four situations: data made before enactment; tests done abroad to meet a foreign rule; data requested after an agency finds existing data insufficient and no non-animal method was practicably available; and specific animal tests requested in writing with a written justification. Each covered agency would have to issue guidance on acceptable non-animal methods within one year and could change its regulations to remove animal-data requirements. Agencies would publish a progress report within one year and then yearly listing animals used, species, test types, waivers issued, and purposes. Agencies could refuse noncompliant animal data and impose civil penalties up to $10,000 for each violation. When no non-animal method exists and no waiver is granted, entities would have to use as few animals as possible and minimize pain, suffering, distress, or lasting harm.