2025-24259Notice

EPA Deems New Chemicals Safe for Production and Use

Published Date: 1/5/2026

Notice

Summary

From July to September 2025, the EPA reviewed new chemicals and their uses to make sure they’re safe for people and the planet. They found that these substances are unlikely to cause harm, so companies can move forward with their plans. This update affects businesses working with new chemicals and helps keep everyone informed about safety and timing.

Analyzed Economic Effects

2 provisions identified: 1 benefits, 1 costs, 0 mixed.

EPA clears two new chemical submissions

Between July 1, 2025 and September 30, 2025, EPA found that certain new chemical submissions are "not likely to present an unreasonable risk". The notice lists case numbers P-24-0139 and P-24-0145; the submitter for a notice with that finding may commence manufacture of the chemical substance even if part of the 90-day review period remains.

90-day premanufacture notice requirement remains

If you plan to manufacture or import a new chemical for a non-exempt commercial purpose, or to start a use EPA designates a "significant new use," you must submit a notice to EPA at least 90 days before you start. This requirement is stated under TSCA section 5(a) and applies to premanufacture notices (PMNs), MCANs, and SNUNs.

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Key Dates

Published Date
1/5/2026

Department and Agencies

Department
Independent Agency
Agency
Environmental Protection Agency
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