Producer
Alchimia S.r.l.
Italian ophthalmic biomaterials manufacturer — RS-OIL ultra-purified silicone oils (1000/1300/2000/5000/5700 cSt), HPF8 perfluorocarbon, vital dyes for vitreoretinal surgery.
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Silicone Oil Tamponades (RS-OIL Line)
50%Perfluorocarbon Liquids (HPF8)
20%Vital Dyes for Vitreoretinal Surgery
30%
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Did you know2024
Brilliant Blue G (BBG), which Alchimia formulates into their Membrane Blue Dual vital dye for staining the Internal Limiting Membrane during macular hole repair surgery, is the same compound as Coomassie Brilliant Blue — the protein stain used in every biochemistry and molecular biology laboratory in the world for SDS-PAGE gel electrophoresis and the Bradford protein assay. Coomassie staining is how scientists visualize protein bands in gel electrophoresis experiments; BBG for eye surgery is the same compound reformulated to pharmaceutical purity for intraocular injection. Furthermore, Brilliant Blue FCF (FD&C Blue No. 1, E133), a structurally similar triphenylmethane dye, is approved as a food colorant used in blue M&Ms, Gatorade, and blue-colored candy. The dye class that colors food and stains lab gels is the same chemical family as the ophthalmic surgical dye that allows retinal surgeons to peel the 4-micron-thick ILM membrane without tearing the underlying macula.
Alchimia S.r.l. ↗Concentration2024
Alchimia, Fluoron GmbH (Germany), and DORC (Netherlands) are the three primary European manufacturers of the complete consumable kit for complex vitreoretinal surgery: silicone oil, perfluorocarbon liquid, and vital dyes. All three are small private companies with single-site manufacturing. No US manufacturer produces the full vitreoretinal consumable kit — Alcon and Bausch + Lomb make silicone oil but rely on European specialty suppliers for vital dyes and PFCL. For European hospitals performing complex retinal surgery (macular hole repair, proliferative vitreoretinopathy, complex detachments), the consumable supply chain runs almost entirely through three small European companies with no domestic US redundancy. Any disruption at the Ulm (Germany), Padua (Italy), or Rotterdam (Netherlands) manufacturing sites would simultaneously affect vitreoretinal surgery supply across Europe and the US.
Alchimia S.r.l. ↗Origin2024
Alchimia S.r.l. is a private Italian company founded in the Veneto region near Padua — Italy's historic home of ophthalmology (the University of Padua's medical school, founded 1222, was where William Harvey discovered blood circulation, and where ophthalmic surgery was pioneered as a discipline). Alchimia developed proprietary ultrapurification and analytical validation technology for silicone polymers and perfluorocarbons to meet CE mark and ISO 10993 biocompatibility requirements for intraocular use. Their RS-OIL silicone oil line covers five viscosity grades — more variants than any competitor — allowing surgeons to select the exact viscosity matched to the specific anatomy and position of a retinal detachment. The company expanded from silicone oils into vital dyes, offering ophthalmologists a single-supplier for the consumables kit used in complex posterior segment procedures.
Alchimia S.r.l. ↗