manufactured · input

Cellulose Triacetate (CTA) Hollow Fiber Membrane

CTA hollow fiber membrane for dialyzers, made from wood-pulp cellulose acetylated with acetic anhydride. CTA dialyzers (Nipro Sureflux, Nipro Cellentia series) are preferred in Japan and parts of Asia for their biocompatibility in patients with certain sensitivities. Toyobo Co. in Iwakuni, Japan is the only commercial manufacturer of CTA dialyzer hollow fiber membranes globally.

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Source countries

2

Companies

1

Goods affected

0

Claims on record

What depends on it

Goods that need this input

1 essential American goods rely on cellulose triacetate (cta) hollow fiber membrane somewhere upstream in their supply chain.

Where it comes from

Source countries

Share of global supply, by country.

CountryShare of supply
JPJapan95%
USUnited States5%

Who makes it

Supplier companies

2 companies produce cellulose triacetate (cta) hollow fiber membrane.

Toyobo Co., Ltd.(3101.T)

HQ JP95% shareSOLE SUPPLIER

Osaka-based Japanese diversified materials conglomerate (TSE: 3101). In 2022, spun out its specialty materials businesses into Toyobo MC Corporation (subsidiary), which produces: ZYLON® (PBO fiber — the world's sole commercial producer), IZANAS® (ultra-high-molecular-weight polyethylene fiber), TSUNOOGA® (high-strength polyethylene), HOLLOSEP® (cellulose triacetate hollow fiber membranes for dialysis and water treatment), VYLON® (polyester resins), BREATHAIR® (3D polyester cushioning). ZYLON PBO fiber (decomposition temperature 650°C, LOI 68) is produced at the Iwakuni Production Center in Iwakuni, Yamaguchi Prefecture. Full-scale ZYLON production began 1998. Toyobo MC is simultaneously the world's only PBO fiber producer AND the world's leading hemodialysis membrane maker — two life-critical medical and safety products from one Japanese specialty chemicals company. Toyobo paid $66M in 2018 to resolve False Claims Act allegations related to defective Zylon-containing bulletproof vests sold to US law enforcement (2003-2018 litigation).

Nipro Corporation(8086.T)

HQ JP

Japanese diversified medical device and pharmaceutical packaging company (TYO: 8086; ~¥500B revenue); headquartered in Osaka. Nipro is the largest pharmaceutical glass vial manufacturer in Japan and a major global supplier, holding an estimated 10-15% of global pharmaceutical glass vial market share. Nipro's pharma glass operations span borosilicate vial production (Nipro Pharma Corporation subsidiary) and medical device manufacturing. Nipro is one of the few manufacturers with both pharmaceutical glass tubing drawing capability AND vial conversion capacity in-house — a vertical integration comparable to SCHOTT Pharma. Major supplier to Japanese domestic pharmaceutical manufacturers; growing export market in Asia, India, and emerging markets. Also the world's largest manufacturer of hemodialysis equipment and supplies.