Propofol Injectable Anesthetic (Diprivan generic)

Lipid emulsion formulation of propofol (2,6-diisopropylphenol) for IV induction and maintenance of general anesthesia and ICU sedation. Required for virtually every surgical procedure and mechanically ventilated ICU patient. During COVID-19 (spring 2020), ICU propofol demand surged ~300-400% as respiratory patients required deep sedation for mechanical ventilation; global shortage ensued. Primary US/EU manufacturers: Fresenius Kabi, Hikma, Pfizer/Hospira, Teva. Propofol formulation requires soy lecithin (lipid emulsion stabilizer) and refined soybean oil — agricultural supply chain inputs.