chemical · input
Pharmaceutical-grade sodium bicarbonate (baking soda) meeting USP specifications for injectable/dialysate applications. Used to prepare the bicarbonate concentrate in all hemodialysis sessions (typical session uses ~350–500g NaHCO3). Church & Dwight (Arm & Hammer) is the dominant North American supplier from their Green River, Wyoming trona-ore mine.
4
Source countries
5
Companies
1
Goods affected
0
Claims on record
What depends on it
1 essential American goods rely on sodium bicarbonate usp (pharmaceutical grade) somewhere upstream in their supply chain.
Where it comes from
Share of global supply, by country.
| Country | Share of supply |
|---|---|
| USUnited States | 60% |
| DEGermany | 15% |
| CNChina | 12% |
| FRFrance | 8% |
Who makes it
5 companies produce sodium bicarbonate usp (pharmaceutical grade).
Consumer and specialty products company; dominant North American pharmaceutical-grade sodium bicarbonate supplier under the ARM & HAMMER brand; two FDA-registered cGMP Drug Establishment manufacturing sites: Green River Wyoming (trona-ore based, primary) and Old Fort Ohio; produces specific "Hemodialysis Grade" sodium bicarbonate meeting USP, ICH Q7, and cGMP requirements; ~60% of North American dialysis-grade sodium bicarbonate market
Wixom, Michigan-based micro-cap ($100M revenue) that is one of only two significant US suppliers of hemodialysis concentrate — the other being Fresenius. Rockwell makes SteriLyte liquid bicarbonate, Trifecta, and other concentrate products. With Fresenius vertically integrated into clinic operators, Rockwell is the sole independent concentrate supplier to non-Fresenius US clinics.
Post-December 2023 split Solvay (retained basic chemicals after Syensqo spinoff); produces Bicar®pharma — the leading European pharmaceutical-grade sodium bicarbonate brand for hemodialysis; API manufactured at Dombasle-sur-Meurthe (France), Torrelavega (Spain), and Map Ta Phut (Thailand); certified GMP and holds CEP (Certificate of European Pharmacopoeia); dominant European/EMEA supplier for dialysis bicarbonate concentrate
Colorado-based trona-ore sodium bicarbonate producer; second-largest US pharmaceutical-grade sodium bicarbonate supplier after Church & Dwight; mining operations in Rifle, Colorado; FDA-registered GMP facility; significant supplier to dialysis concentrate manufacturers as an alternative to Church & Dwight Arm & Hammer brand
Indian chemical company (Tata Group); claimed ~20% global STPP market share by some market research. Produces sodium carbonate (soda ash), sodium bicarbonate, STPP, and specialty chemicals at plants in India (Mithapur, Gujarat), UK (Winnington, Cheshire), and Kenya. Tata Chemicals' STPP for food and industrial use. Also known for producing the world's most affordable water purifier (Swach, using rice husk ash nanotechnology) — a Tata social innovation using chemical manufacturing expertise for rural India water access.
