chemical · input

SPPS Reagents — Protected Amino Acids, Resins & C18 Fatty-Diacid Side Chain

Specialized solid-phase peptide synthesis feedstock: Fmoc-protected amino acids (including unnatural Aib), synthesis resins, Ado spacers, and the C18 fatty-diacid acylation reagent. Not interchangeable with commodity amino-acid suppliers.

3

Source countries

7

Companies

1

Goods affected

0

Claims on record

What depends on it

Goods that need this input

1 essential American goods rely on spps reagents — protected amino acids, resins & c18 fatty-diacid side chain somewhere upstream in their supply chain.

Where it comes from

Source countries

Share of global supply, by country.

CountryShare of supply
CNChina28%
DEGermany/Europe14%
CHSwitzerland12%

Who makes it

Supplier companies

7 companies produce spps reagents — protected amino acids, resins & c18 fatty-diacid side chain.

GL Biochem (Shanghai)

HQ CN18% share

One of the world's largest peptide & amino-acid makers; 200+ Fmoc unnatural amino-acid SKUs.

Bachem Holding AG

HQ CH12% share

Swiss peptide CDMO; largest independent peptide API manufacturer globally; $1B+ expansion at Bubendorf Switzerland; key GLP-1 API supplier for generics and biosimilar programs

Merck KGaA (MilliporeSigma in US)(MRK)

HQ DE8% share

German multinational producing the Hi-Flow Plus nitrocellulose membrane — one of the two industry-standard LFA membranes globally. Received a €121M US DoD/HHS contract to build the first US lateral flow membrane facility in Sheboygan, WI (2022) to reduce concentration risk in Cork, Ireland.

Chengdu Kelong Chemical

HQ CN6% share

Chinese volume producer of Fmoc-protected amino acids.

Iris Biotech GmbH

HQ DE6% share

Specialist supplier of Fmoc-protected building blocks, SPPS reagents and peptidomimetics.

ZY Biochem

HQ CN4% share

Chinese Fmoc amino-acid / peptide reagent maker.

CordenPharma

HQ CH

Swiss CDMO operating European and US API manufacturing sites; primary lipid partner for Moderna; manufactures SM-102 and full LNP lipid component portfolio including ionizable, PEGylated, phosphocholine, and plant sterols; claims largest complex lipid capacity globally