2025-00730NoticeWallet

Diisononyl Phthalate (DINP); Risk Evaluation Under the Toxic Substances Control Act; Notice of Availability

Published Date: 1/15/2025

Notice

Summary

The EPA has finished checking the safety of a chemical called DINP and found it can harm people’s health. Companies that make, use, or handle DINP will soon face new rules to keep everyone safe. These changes could affect how DINP is made and used, so businesses should get ready to follow the new safety steps.

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Analyzed Economic Effects

4 provisions identified: 2 benefits, 2 costs, 0 mixed.

Spray-Use Workers Face Health Risk

EPA identified that spray application of adhesives, sealants, or paints and coatings containing DINP can create high inhalation exposure and that female workers of reproductive age face developmental toxicity from acute inhalation; workers also face liver effects from chronic exposures. EPA says it will focus risk management on the conditions of use that most contribute to that risk.

EPA: DINP Unsafe — Rules Coming

The EPA says diisononyl phthalate (DINP, CASRN 28553-12-0 and 68515-48-0) poses an unreasonable risk to human health and must begin risk management under TSCA section 6(a). EPA will propose regulatory actions affecting manufacture (including import), processing, distribution in commerce, commercial use, and disposal — companies that make, import, or sell DINP should prepare for new requirements. DINP production volumes reported: CASRN 28553-12-0 was 100–250 million lb in 2015 and 50–100 million lb in 2019; CASRN 68515-48-0 was 100–250 million lb in 2015 and 100 million–1 billion lb in 2019.

Adult Consumers: Liver-Effect Risk Identified

EPA found the chronic liver effects associated with DINP are relevant to adult consumers and the adult general population (but not to infants and children). This finding means EPA may take steps that could change consumer products or their availability to address adult exposure.

Upstream Firms Could Be Regulated

EPA may regulate upstream activities (for example, processing or distribution in commerce) to address downstream consumer or worker uses that drive the unreasonable risk, even if those upstream activities were not identified as driving the risk. That means importers, processors, and distributors could face restrictions or requirements.

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Key Dates

Published Date
1/15/2025

Department and Agencies

Department
Independent Agency
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