§284k Clinical research

Findings and Purpose Pub. L. 106–505, title II, § 202, Nov. 13, 2000, 114 Stat. 2325, provided that: “(a) Findings.—Congress makes the following findings:“(1) Clinical research is critical to the advancement of scientific knowledge and to the development of cures and improved treatment for disease. “(2) Tremendous advances in biology are opening doors to new insights into human physiology, pathophysiology and disease, creating extraordinary opportunities for clinical research. “(3) Clinical research includes translational research which is an integral part of the research process leading to general human applications. It is the bridge between the laboratory and new methods of diagnosis, treatment, and prevention and is thus essential to progress against cancer and other diseases. “(4) The United States will spend more than $1,200,000,000,000 on health care in 1999, but the Federal budget for health research at the National Institutes of Health was $15,600,000,000 only 1 percent of that total. “(5) Studies at the Institute of Medicine, the National Research Council, and the National Academy of Sciences have all addressed the current problems in clinical research. “(6) The Director of the National Institutes of Health has recognized the current problems in clinical research and appointed a special panel, which recommended expanded support for existing National Institutes of Health clinical research programs and the creation of new initiatives to recruit and retain clinical investigators. “(7) The current level of training and support for health professionals in clinical research is fragmented, undervalued, and underfunded. “(8) Young investigators are not only apprentices for future positions but a crucial source of energy, enthusiasm, and ideas in the day-to-day research that constitutes the scientific enterprise. Serious questions about the future of life-science research are raised by the following:“(A) The number of young investigators applying for grants dropped by 54 percent between 1985 and 1993. “(B) The number of physicians applying for first-time National Institutes of Health research project grants fell from 1226 in 1994 to 963 in 1998, a 21 percent reduction. “(C) Newly independent life-scientists are expected to raise funds to support their new research programs and a substantial proportion of their own salaries. “(9) The following have been cited as reasons for the decline in the number of active clinical researchers, and those choosing this career path:“(A) A medical school graduate incurs an average debt of $85,619, as reported in the Medical School Graduation Questionnaire by the Association of American Medical Colleges (AAMC). “(B) The prolonged period of clinical training required increases the accumulated debt burden. “(C) The decreasing number of mentors and role models. “(D) The perceived instability of funding from the National Institutes of Health and other Federal agencies. “(E) The almost complete absence of clinical research training in the curriculum of training grant awardees. “(F) Academic Medical Centers are experiencing difficulties in maintaining a proper environment for research in a highly competitive health care marketplace, which are compounded by the decreased willingness of third party payers to cover health care costs for patients engaged in research studies and research procedures. “(10) In 1960, general clinical research centers were established under the Office of the Director of the National Institutes of Health with an initial appropriation of $3,000,000. “(11) Appropriations for general clinical research centers in fiscal year 1999 equaled $200,500,000. “(12) Since the late 1960s, spending for general clinical research centers has declined from approximately 3 percent to 1 percent of the National Institutes of Health budget. “(13) In fiscal year 1999, there were 77 general clinical research centers in operation, supplying patients in the areas in which such centers operate with access to the most modern clinical research and clinical research facilities and technologies. “(b) Purpose.—It is the purpose of this title [see

of 2000

note set out under section 201 of this title] to provide additional support for and to expand clinical research programs.” Oversight by GAO Pub. L. 106–505, title II, § 207, Nov. 13, 2000, 114 Stat. 2330, provided that, not later than 18 months after Nov. 13, 2000, the Comptroller General was to submit to Congress a report describing the extent to which the National Institutes of Health had complied with the

made by title II of Pub. L. 106–505.