Producer
Purolite (Ecolab Life Sciences)
Purolite Corporation (Philadelphia PA; acquired by Ecolab Inc. NYSE: ECL for $3.7B in 2021; now Ecolab Life Sciences division) manufactures Praesto Protein A affinity resins — synthetic polymer bead-based Protein A resins designed for cost-competitive mAb purification. Purolite's Praesto AP (agarose-based) and Praesto Jetted A50 (synthetic polymer) resins offer manufacturers an alternative to Cytiva and Merck KGaA products. Purolite has manufacturing in Wales (Pontyclun UK) and Bucks County Pennsylvania. Ecolab's acquisition of Purolite for $3.7B signaled that industrial water treatment companies (Ecolab's core business) view bioprocess consumables as an adjacency to their hygiene and process chemistry businesses. Ecolab/Purolite competes with Cytiva and Merck KGaA in Protein A resins while Ecolab's water treatment division simultaneously serves the same biopharmaceutical manufacturing facilities for their utility water systems — a vertically adjacent position across multiple biomanufacturing consumable categories.
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Protein A Affinity Resins (Praesto)
42%Ion Exchange Resins (Water & Pharma)
35%Specialty Resins (Nuclear, Condensate)
15%Chromatography Media
8%
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Did you know2024
Ecolab is tracked as a water treatment and sanitation company (serving food/beverage factories, restaurants, hotels, and hospitals), but through Purolite it is now also a critical supplier to the biopharmaceutical supply chain via Protein A resins used to purify monoclonal antibodies. Additionally, Purolite's ion exchange resins are used in nuclear power plant condensate polishing and nuclear waste water treatment — making Ecolab simultaneously a player in food safety sanitation, biopharma manufacturing, and nuclear energy water management supply chains. Three entirely separate regulated industries (food/hospitality hygiene, biopharmaceutical manufacturing, nuclear power operations) all trace back to the same Ecolab parent company through different Purolite/Ecolab product lines.
Ecolab Inc ↗Origin2023
Purolite Corporation was founded in 1981 in Philadelphia as a specialty ion exchange resin manufacturer, focused on producing resins for industrial water treatment (water softening, deionization) and pharmaceutical applications. The company expanded into bioprocess-specific Protein A affinity resins (Praesto brand) as the biopharmaceutical monoclonal antibody industry grew. Ecolab Inc. — primarily known as a water treatment, hygiene, and sanitation company for foodservice, healthcare, and industrial customers — acquired Purolite for $3.7 billion in 2021, integrating it as "Ecolab Life Sciences." The acquisition transformed a restaurant/hospital hygiene company into a biopharma supply chain company.
Purolite / Ecolab Life Sciences ↗